Principles of Endocrine Pharmacology

Authors: Thomas, John A., Keenan, Edward J.

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About this book

The authors have provided an overview of the relationships between hormones that are physiologic constituents of the body as well as their pharmacologic use in replacement therapies and related endocrine dys­ function. Principles of Endocrine Pharmacology concerns itself with the ther­ apeutic use of hormones, and hormone like substances, or drugs that can act either by suppressing or enhancing the metabolism of certain glands of internal secretion. Other drugs used for nonendocrine ther­ apies can likewise affect the endocrine system. Endocrine pharmacology emerged in the early 1900s with the use of crude pituitary extracts. By the mid-1900s several investigators had isolated and begun to synthesize hormones or hormonelike substances. Recognizing the limited supply of hormones that could be obtained both from animal sources and human autopsy material, the search for so­ called hormone substitutes also began early in the 1900s. Recently, re­ combinant DNA technologies have been used to provide alternative therapeutic sources of human insulin and human growth hormone. Aside from insulin, perhaps no other use of hormonally-active sub­ stance is better exemplified by those drugs which affect fertility. The synthesis of an orally-effective steroid represented one of the first major breakthroughs in the chemical suppression of ovulation. Since the orally­ active 19-norsteroids were introduced in the 1950s, several oral contra­ ceptive steroid preparations have been marketed. Indeed, the advent of oral contraceptives for birth control has led to a renewed interest in endocrine pharmacology.

Table of contents (11 chapters)

  • Introduction and General Mechanisms of Hormonal Actions

    Thomas, John A. (et al.)

    Pages 1-14

  • Pharmacology of Adenohypophyseal Hormones

    Thomas, John A. (et al.)

    Pages 15-42

  • Posterior Pituitary Hormones, Oxytocics, and Prostaglandins

    Thomas, John A. (et al.)

    Pages 43-68

  • Thyroid and Antithyroidal Drugs

    Thomas, John A. (et al.)

    Pages 69-91

  • Parathyroid Hormone and Calcitonin

    Thomas, John A. (et al.)

    Pages 93-109

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4684-5036-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-0-306-42143-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Principles of Endocrine Pharmacology
Authors
Copyright
1986
Publisher
Springer US
Copyright Holder
Plenum Publishing Corporation
eBook ISBN
978-1-4684-5036-1
DOI
10.1007/978-1-4684-5036-1
Softcover ISBN
978-0-306-42143-3
Edition Number
1
Number of Pages
310
Topics