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Cellular and Molecular Biology of Neuronal Development

Authors: Black, Ira

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  • ISBN 978-1-4613-2717-2
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Hardcover $139.99
price for USA in USD
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About this book

A central problem in neurobiology concerns mechanisms that generate the pro­ found diversity and specificity of the nervous system. What is the substance of diversification and specificity at the molecular, cellular, and systems levels? 4 How, for example, do 1011 neurons each form approximately 10 interconnec­ tions, allowing normal physiological function? How does disruption of these processes result in human disease? These proceedings represent the efforts of molecular biologists, embryologists, neurobiologists, and clinicians to approach these issues. in this volume are grouped by subject to present the varieties The chapters of methods used to approach each individual area. Section I deals with embry­ ogenesis and morphogenesis of the nervous system. In Chapter 3, Weston and co-workers describe the use of monoclonal antibodies that recognize specific neuronal epitopes (including specific gangliosides) for the purpose of defining heterogeneity in the neural crest, an important model system. Immunocyto­ chemical analysis reveals the existence of distinct sUbpopulations within the crest at extremely early stages; cells express neuronal or glial binding patterns at the time of migration. Consequently, interactions with the environment may select for predetermined populations. Le Douarin reaches similar conclusions in Chapter 1 by analyzing migratory pathways and developmental potentials in crest of quail-

Table of contents (22 chapters)

  • A Model for Cell-Line Divergence in the Ontogeny of the Peripheral Nervous System

    Douarin, Nicole M.

    Pages 3-28

  • Emergence of Neuronal and Glial Cell Lineages in Primate Brain

    Rakic, Pasko

    Pages 29-50

  • Heterogeneity in Neural Crest Cell Populations

    Weston, James A. (et al.)

    Pages 51-62

  • The First Growth Cones in the Central Nervous System of the Grasshopper Embryo

    Bastiani, Michael J. (et al.)

    Pages 63-84

  • Surface-Bound and Released Neuronal Glycoconjugates

    Patterson, Paul H.

    Pages 87-94

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4613-2717-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-0-306-41550-0
  • Free shipping for individuals worldwide
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $109.99
price for USA in USD
  • ISBN 978-1-4612-9686-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cellular and Molecular Biology of Neuronal Development
Authors
Copyright
1984
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4613-2717-2
DOI
10.1007/978-1-4613-2717-2
Hardcover ISBN
978-0-306-41550-0
Softcover ISBN
978-1-4612-9686-7
Edition Number
1
Number of Pages
XXVI, 363
Number of Illustrations and Tables
148 b/w illustrations
Topics