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Environmental Science Research

Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III

Editors: Waters, Michael D. (Ed.)

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About this book

In the four years since the 1978 Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures the use of short-term bioassays to evaluate potential health hazards of complex environmental mixtures has substantially increased. Increased research activity has been particularly noticeable in mobile source emissions, where initial observations on the mutagenic activity of diesel particulate extracts reported at the 1978 symposium stimulated the development of major research programs in government and industry. In the absence of appropriate reference materials, the U.S. Environmental Protection Agency initiated comparative genotoxicity studies to determine the relative mutagenic and carcinogenic activity and, ultimately, the potential human health risk due to exposure to various complex emission products. Among the materials investigated were those of known health risk, such as coke oven and roofing tar emissions and cigarette smoke condensates, and those of unknown hazard, such as exhaust from diesel-and gasoline-powered vehicles. Studies on diesel emission products proved useful in short­ term bioassay development, as the diesel exhaust extracts were genetically active with low cellular toxicity and could be obtained in relatively large quantities. Availability of such samples aided chemical characterization, and it was eventually determined that the nitro-polynuclear aromatic hydrocarbons were among the mutagenic components of diesel exhaust particulate.

Table of contents (37 chapters)

Table of contents (37 chapters)
  • Some Aspects of Mutagenicity Testing of the Particulate Phase and the Gas Phase of Diluted and Undiluted Automobile Exhaust

    Pages 3-16

    Rannug, Ulf (et al.)

  • Source Assessment Sampling System (SASS) Versus Dilution Tunnel Sampling

    Pages 17-26

    Merrill, Raymond G., Jr. (et al.)

  • Preparation of Hazardous and Complex Samples for Ecological Testing

    Pages 27-38

    Duke, Kenneth M. (et al.)

  • Sample Collection and Preparation Methods Affecting Mutagenicity and Cytotoxicity of Coal Fly Ash

    Pages 39-58

    Mumford, Judy L. (et al.)

  • The Use of Short-Term Bioassays to Monitor the Environmental Impact of Land Treatment of Hazardous Wastes

    Pages 59-78

    Donnelly, Kirby C. (et al.)

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-1-4613-3611-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $99.00
price for USA in USD
  • ISBN 978-0-306-41191-5
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4613-3613-6
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III
Editors
  • Michael D. Waters
Series Title
Environmental Science Research
Series Volume
27
Copyright
1983
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4613-3611-2
DOI
10.1007/978-1-4613-3611-2
Hardcover ISBN
978-0-306-41191-5
Softcover ISBN
978-1-4613-3613-6
Edition Number
1
Number of Pages
589
Topics

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