Overview
- Advances made in forty years of radiopharmaceutical development based on Technetium
- Good manufacturing practice (GMP) and the official quality standards stated for radiopharmaceuticals are part of the quality assurance
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Table of contents(12 chapters)
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Part I
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Part II
About this book
Radioactive drug development is a multi-disciplinary task, therefore, in a concerted effort, dedicated scientists and experts from different fields of specialisation have contributed to this book. It is presented in two sections. Section 1 contains basic principles and methods used for analysis, information on the chemistry of technetium and on radiopharmaceuticals labelled with technetium-99m, the characteristics of the 99 Mo/99mTc-generator, of 'kits' and formulations for in-vitro labelling, and special safety aspects for in-vivo labelling of blood cells. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affecting in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients.
Reviews
From the reviews:
"This nicely organized and clearly illustrated book provides an up-to-date resource for radiopharmacists and nuclear medicine physicians who compound and prescribe 99mTc-labeled radiopharmaceuticals. Radiochemists and those concerned with regulatory affairs also will be interested, and the book could be used as a primary text in nuclear medicine training programs. This outstanding book fills a void and is the first compilation of its kind in many years. We recommend it with the highest enthusiasm." (Susan Z. Lever and John R. Lever, Journal of Nuclear Medicine, May, 2009)
Editors and Affiliations
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Department of Medicinal/Pharmaceutical Chemistry, University of Vienna, Vienna, Austria
Ilse Zolle
Bibliographic Information
Book Title: Technetium-99m Pharmaceuticals
Book Subtitle: Preparation and Quality Control in Nuclear Medicine
Editors: Ilse Zolle
DOI: https://doi.org/10.1007/978-3-540-33990-8
Publisher: Springer Berlin, Heidelberg
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2007
Hardcover ISBN: 978-3-540-33989-2Published: 07 November 2006
Softcover ISBN: 978-3-642-07050-1Published: 14 October 2010
eBook ISBN: 978-3-540-33990-8Published: 28 January 2007
Edition Number: 1
Number of Pages: XX, 345
Number of Illustrations: 65 b/w illustrations, 1 illustrations in colour
Topics: Imaging / Radiology, Nuclear Medicine