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Medicine - Pathology | Medical Molecular Morphology

Medical Molecular Morphology

Medical Molecular Morphology

Editor-in-Chief: Takao Senda

ISSN: 1860-1480 (print version)
ISSN: 1860-1499 (electronic version)

Journal no. 795

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22 June 2017

Instructions for Authors

Medical Molecular Morphology

Revised June 22, 2017

Manuscript submission 

Online manuscript submission

Authors should submit their manuscripts online. Electronic submission substantially reduces the editorial processing and reviewing times and shortens overall publication times. Please log in directly at:http://www.editorialmanager.com/mmmo and upload all of your manuscript files following the instructions.

Prerequisites for publication 

A copy of the certification form included in each issue must be submitted with the manuscript. The editorial board decides whether to accept or reject submitted papers in consultation with at least two referees.

Disclosure of confl icts of interest (COI) 

When a manuscript is submitted, authors must disclose any financial relationships they have with business enterprises or for-profit corporate organizations (hereafter referred to as 'Commercial Entities') regarding the subjects or materials treated in the research, if the amount exceeds the criteria
specified below.
1) Position on the advisory board or board of directors at one or more Commercial Entity, if the compensation from one Commercial Entity exceeds ¥1,000,000 per year.
2) Equity ownership, if the profit from one Commercial Entity exceeds ¥1,000,000 per year.
3) Patent royalties from Commercial Entities, if the royalty fee from one Commercial Entity exceeds ¥1,000,000 per year.
4) Honoraria for speaking paid by one Commercial Entity, if the amount exceeds ¥500,000 per year.
5) Remuneration for writing paid by one Commercial Entity, if the amount exceeds ¥500,000 per year.
6) Research grants provided by one Commercial Entity, if the amount exceeds ¥1,000,000 per year.
7) Belonging to endowed departments provided by Commercial Entities.
If there is no such COI, the authors should make a statement as follows: The authors declare that they have no confl icts of interest.
These COI-related statements will appear after the Acknowledgments.

For Clinical Studies 

If materials used in the study are from patients at clinics, it should be stated in the text that the study has been reviewed and approved by the ethics committee for clinical research in the research institutes where the study has been performed, accompanied by the number for the approval.

Types of articles 

Medical Molecular Morphology welcomes articles on basic or clinical research in the fields of cell biology, molecular biology, and medical, veterinary, and dental sciences using techniques for structural research such as electron microscopy, confocal laserscanning microscopes, enzyme histochemistry, immunohistochemistry, X-ray microanalysis, in-situ hybridization, and computer-based 3D reconstruction.
Articles may be in the form of original papers, reviews, case reports, or letters. The maximum length for each type of article is 10, 15, 5, and 1 printed pages, respectively.

Manuscripts in electronic form 

Complete manuscripts, including tables and figures, must be supplied in MS Word format; the abstract, text, references, tables and figure legends must be typed double-space with wide margins. A complete list of submitted materials must accompany each manuscript. Incomplete or improperly prepared manuscripts will be returned to the authors without review.
A separate title page should be provided. The abstract, text, acknowledgments, references, tables, legends and figures should begin on separate pages and follow in that order. Standard abbreviations and units should be used. Abbreviations should be defined the first time they are mentioned, and their use in the title and abstract should be avoided.
The generic names of drugs and chemicals should be used.
All manuscripts must be written in English.
Authors who are not fl uent in English must seek the assistance of a colleague who is a native English speaker and is familiar with the field of work. Manuscripts that have been extensively modified in the editorial process will be returned to the authors for retyping.
For vector graphics figures, the preferred format is EPS; for halftones, please use TIFF format. MS Office files are also acceptable.
All files should be uploaded in the online submission system.

Title page 

Titles should be brief, specific, and informative.
Include the full names of authors; academic affiliation; address to which proofs are to be sent, including a fax number, telephone number, and e-mail address; and 5–7 key words or phrases for indexing. Key words in the title should be included.


A concise description (not more than 200 words) of the purpose, methods, results, and conclusions is required.


The text of experimental articles should be divided into the following sections:
introduction, materials and methods, results, discussion, and conclusion.


Number references consecutively in the order cited in the text, not alphabetically.
The accuracy of reference data is the authors’ responsibility. Personal communications and unpublished data should not be included in the reference list but may be cited in parentheses in the text. If such a citation is from someone other than the authors, a letter should be submitted in which the direct quotation is given with the signature of its author. In the reference list, provide
inclusive page numbers for all references and give the names of all authors (the use of “et al.” is unacceptable). Journal titles should be abbreviated according to the ISSN List of Title Word Abbreviations (http://www.issn.org/services/online-services/access-to-the-ltwa/). Reference citations in the text should be identified by numbers in square brackets, e.g., Abdelatif et al. [1], Matsuda and Ichida [2], and Morson [3].
1. Abdelatif OMA, Khankhanian NK, Crosby JH, Chamberlain CR Jr, Seigler MM, Tom GD (1989) Malignant fibrous istiocytoma and malignant melanoma: the role fimmunohistochemistry and electron microscopy in differential diagnosis. Mod Pathol 2:477–485
2. Matsuda Y, Ichida T (2006) p16 and p27 are functionally correlated during the progress of hepatocarcinogenesis. Med Mol Morphol 39:169–175
3. Morson PC (1975) Pathology of ulcerative colitis. In: Kirsner JB, Shorter RG (eds) Inflammatory bowel disease. Lea and Febiger, Philadelphia, pp 167–181


Should be cited in the text. Each table should be given a number and a brief informative title and should appear on a separate page.
Explain in footnotes all abbreviations used.


Line art
- Definition: Black and white graphic with no shading.
- Do not use faint lines and/or lettering and check that all lines and lettering within the figures are legible at final size.
- All lines should be at least 0.1 mm (0.3 pt) wide.
- Scanned line drawings and line drawings in bitmap format should have a minimum resolution of 1200 dpi.
- Vector graphics containing fonts must have
Halftone art
- Definition: Photographs, drawings, or paintings with fine shading, etc.
- If any magnification is used in the photographs, indicate this by using scale bars within the figures themselves.
- Halftones should have a minimum resolution of 300 dpi.
Combination art
- Definition: a combination of halftone and line art, e.g., halftones containing line drawing, extensive lettering, color diagrams, etc.
- Combination artwork should have a minimum resolution of 600 dpi.
Color art
- Color art is free of charge for online and print publication.
- Color illustrations should be submitted as RGB (8 bits per channel).
Figure lettering
- To add lettering, it is best to use Helvetica or Arial (sans serif fonts).
- Keep lettering consistently sized throughout your final-sized artwork, usually about 2–3 mm (8–12 pt).
- Variance of type size within an illustration should be minimal, e.g., do not use 8-pt type on an axis and 20-pt type for the axis label.
- Avoid effects such as shading, outline letters, etc.
- Do not include titles or captions into your illustrations.
Figure numbering
- All figures are to be numbered using Arabic numerals.
- Figures should always be cited in the text in consecutive numerical order.
- Figure parts should be denoted by lowercase letters (a, b, c, etc.).
- If an appendix appears in your article/chapter and it contains one or more figures, continue the consecutive numbering of the main text.
Do not number the appendix figures, “A1, A2, A3, etc.” Figures in online appendices (Electronic supplementary Material) should, however, be numbered separately.
Figure captions
- Each figure should have a concise caption describing accurately what the fi ure depicts. Include the captions in the text file of the manuscript, not in the figure file.
- Figure captions begin with the term Fig. in bold type, followed by the figure number, also in bold type.
- No punctuation is to be included after the number, nor is any punctuation to be placed at the end of the caption.
- Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs.
- Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption.
If you include figures that have already been published elsewhere, you must obtain permission from the copyright owner(s) for both the print and online format. Please be
aware that some publishers do not grant electronic rights for free and that Springer will not be able to refund any costs that may have occurred to receive these permissions.
In such cases, material from other sources should be used.
In order to give people of all abilities and disabilities access to the content of your figures, please make sure that
- All figures have descriptive captions (blind users could then use a text-tospeech software or a text-to-Braille hardware)
- Patterns are used instead or in addition to colors for conveying information (colorblind users would then be able to distinguish the visual elements)
- Any figure lettering has a contrast ratio of at least 4.5:1.

Electronic Supplementary Material 

Electronic supplementary material will be published in the online version only. It may consist of
- Information that cannot be printed: animations, video clips, sound recordings
- Information that is more convenient in electronic form: sequences, spectral data, etc.
- Large original data, e.g. additional tables, illustrations, etc.
- Supply all supplementary material in standard file formats.
- To accommodate user downloads, please keep in mind that larger-sized files may require very long download times and that some users may experience other problems during downloading.
Audio, video, and animations
- Always use MPEG-1 (.mpg) format.
- Text and Presentations
- Submit your material in PDF format; .doc or .ppt files are not suitable for long-term viability.
- A collection of figures may also be combined in a PDF file.
- Spreadsheets should be converted to PDF if no interaction with the data is intended.
- If the readers should be encouraged to make their own calculations, spreadsheets should be submitted as .xls files (MS Excel).
Specialized formats
- Specialized formats such as .pdb (chemical), .wrl (VRML), .nb (Mathematica notebook), and .tex can also be supplied.
- Collecting Multiple Files
- It is possible to collect multiple files in a .zip or .gz file.
- If supplying any supplementary material, the text must make specific mention of the material as a citation, similar to that of figures and tables.
- Refer to the supplementary files as “Online Resource”, e.g., “... as shown in the animation (Online Resource 3)”, “... additional data are given in Online Resource 4”.
- Name the files consecutively, e.g. “ESM_3. mpg”, “ESM_4.pdf”.
- For each supplementary material, please supply a concise caption describing the content of the file.
Processing of supplementary files
- Electronic supplementary material will be published as received from the author without any conversion, editing, or
In order to give people of all abilities and disabilities access to the content of your supplementary files, please make sure that
- The manuscript contain a descriptive caption for each supplementary material
- Video files do not contain anything that fl ashes more than three times per second (so that users prone to seizures caused by such effects are not put at risk).

After acceptance 

Upon acceptance of your article you will receive a link to the special Author Query Application at Springer’s web page where you can sign the Copyright Transfer Statement
Once the Author Query Application has been completed, your article will be processed and you will receive the proofs.
You will also receive a separate e-mail for ordering offprints and OpenChoice.


In addition to the normal publication process (whereby an article is submitted to the journal and access to that article is granted to customers who have purchased a subscription), Springer provides an alternative publishing option: Springer Open Choice. A Springer Open Choice article receives all the benefits of a regular subscription-based article, but in addition is made available publicly through Springer’s online platform SpringerLink.
Springer Open Choice [http://springer.com/openchoice]

Copyright transfer 

Authors will be asked to transfer copyright of the article to the Japanese Society for Clinical Molecular Morphology (or grant the Japanese Society for Clinical Molecular Morphology exclusive publication and dissemination rights). This will ensure the widest possible protection and dissemination of information under copyright laws.


Offprints can be ordered by the corresponding author. Offprints of each paper are available in lots of 50.

Page charge 

For reviews, free of page charge.
For original papers, case reports and letters, the page charge is ¥10,000 per printed page.
If the first author is a member of the Society, up to two printed pages are free of charge.
The charge for additional printed pages is ¥10,000 per page.

Color illustrations 

Online and print publication of color illustrations is free
of charge.

Proof reading 

The purpose of the proof is to check for typesetting or conversion errors and the completeness and accuracy of the text, tables and figures. Substantial changes in content, e.g., new results, corrected values, title and authorship, are not allowed without the approval of the Editor.
After online publication, further changes can only be made in the form of an Erratum, which will be hyperlinked to the article.

Online fi rst 

The article will be published online after receipt of the corrected proofs. This is the official first publication citable with the DOI. After release of the printed version, the paper can also be cited by issue and page numbers.

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For authors and editors

  • Journal Citation Reports®
    2017 Impact Factor
  • 1.217
  • Aims and Scope

    Aims and Scope


    Medical Molecular Morphology is an international forum for researchers in both basic and clinical medicine to present and discuss new research on the structural mechanisms and the processes of health and disease at the molecular level. The structures of molecules, organelles, cells, tissues, and organs determine their normal function. Disease is thus best understood in terms of structural changes in these different levels of biological organization, especially in molecules and molecular interactions as well as the cellular localization of chemical components. Medical Molecular Morphology welcomes articles on basic or clinical research in the fields of cell biology, molecular biology, and medical, veterinary, and dental sciences using techniques for structural research such as electron microscopy, confocal laser scanning microscopy, enzyme histochemistry, immunohistochemistry, radioautography, X-ray microanalysis, and in situ hybridization.

    Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.

    Reports of animal experiments must state that the "Principles of laboratory animal care"(NIH publication No. 86-23, revised 1985) were followed.

    The Editor-in-Chief reserves the right to reject manuscripts that do not comply with the above-mentioned requirements. The author will be held responsible for false statements or for failure to fulfil the above-mentioned requirements.


  • Submit Online
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    How to submit your manuscript


  • Instructions for Authors

    Instructions for Authors


  • Certification Form (pdf, 32 kB)
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    English Language Editing


  • Author Academy: Training for Authors
  • Copyright Information

    Copyright Information


    For Authors

    Submission of a manuscript implies: that the work described has not been published before (except in form of an abstract or as part of a published lecture, review or thesis); that it is not under consideration for publication elsewhere; that its publication has been approved by all co-authors, if any, as well as – tacitly or explicitly – by the responsible authorities at the institution where the work was carried out.

    Author warrants (i) that he/she is the sole owner or has been authorized by any additional copyright owner to assign the right, (ii) that the article does not infringe any third party rights and no license from or payments to a third party is required to publish the article and (iii) that the article has not been previously published or licensed. The author signs for and accepts responsibility for releasing this material on behalf of any and all co-authors. Transfer of copyright to the Japanese Society for Clinical Molecular Morphology becomes effective if and when a Copyright Transfer Statement is signed or transferred electronically by the corresponding author. After submission of the Copyright Transfer Statement signed by the corresponding author, changes of authorship or in the order of the authors listed will not be accepted by Springer.

    The copyright to this article, including any graphic elements therein (e.g. illustrations, charts, moving images), is assigned for good and valuable consideration to the Japanese Society for Clinical Molecular Morphology effective if and when the article is accepted for publication and to the extent assignable if assignability is restricted for by applicable law or regulations (e.g. for U.S. government or crown employees).

    The copyright assignment includes without limitation the exclusive, assignable and sublicensable right, unlimited in time and territory, to reproduce, publish, distribute, transmit, make available and store the article, including abstracts thereof, in all forms of media of expression now known or developed in the future, including pre- and reprints, translations, photographic reproductions and microform. Springer may use the article in whole or in part in electronic form, such as use in databases or data networks for display, print or download to stationary or portable devices. This includes interactive and multimedia use and the right to alter the article to the extent necessary for such use.

    Authors may self-archive the Author’s accepted manuscript of their articles on their own websites. Authors may also deposit this version of the article in any repository, provided it is only made publicly available 12 months after official publication or later. He/she may not use the publisher's version (the final article), which is posted on SpringerLink and other Springer websites, for the purpose of self-archiving or deposit. Furthermore, the Author may only post his/her version provided acknowledgement is given to the original source of publication and a link is inserted to the published article on Springer's website. The link must be accompanied by the following text: "The final publication is available at link.springer.com”.

    Prior versions of the article published on non-commercial pre-print servers like arXiv.org can remain on these servers and/or can be updated with Author's accepted version. The final published version (in pdf or html/xml format) cannot be used for this purpose. Acknowledgement needs to be given to the final publication and a link must be inserted to the published article on Springer's website, accompanied by the text "The final publication is available at link.springer.com". Author retains the right to use his/her article for his/her further scientific career by including the final published journal article in other publications such as dissertations and postdoctoral qualifications provided acknowledgement is given to the original source of publication.

    Author is requested to use the appropriate DOI for the article. Articles disseminated via springer.link.com are indexed, abstracted and referenced by many abstracting and information services, bibliographic networks, subscription agencies, library networks, and consortia.

    For Readers

    While the advice and information in this journal is believed to be true and accurate at the date of its publication, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may have been made. The publisher makes no warranty, express or implied, with respect to the material contained herein.

    All articles published in this journal are protected by copyright, which covers the exclusive rights to reproduce and distribute the article (e.g., as offprints), as well as all translation rights. No material published in this journal may be reproduced photographically or stored on microfilm, in electronic data bases, video disks, etc., without first obtaining written permission from the Japanese Society for Clinical Molecular Morphology. The use of general descriptive names, trade names, trademarks, etc., in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

    Springer has partnered with Copyright Clearance Center’s RightsLink service to offer a variety of options for reusing Springer content. For permission to reuse our content please locate the material that you wish to use on SpringerLink.com or on SpringerImages.com and click on the permissions link or go to copyright.com and enter the title of the publication that you wish to use. For assistance in placing a permission request, Copyright Clearance Center can be connected directly via phone: +1-855-239-3415, fax: +1-978-646-8600, or e-mail: info@copyright.com.


    © the Japanese Society for Clinical Molecular Morphology

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