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Biological and Medical Physics, Biomedical Engineering

Radiation Damage in Biomolecular Systems

Editors: García Gómez-Tejedor, Gustavo, Fuss, Martina Christina (Eds.)

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  • Reports a worldwide study on the mechanisms of radiation induced damage at the molecular level
  • Addresses the biomedical aspects of radiation effects and reviews DNA damage repair
  • Describes novel developments in radiation research and radiotherapy
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  • ISBN 978-94-007-2564-5
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About this book

Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection.
Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada,  the USA and Australia.
This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems.

An extensive Part I deals with recent experimental and theoretical findings on radiation induced damage at the molecular level. It includes many contributions on electron and positron collisions with biologically relevant molecules. X-ray and ion interactions are also covered. Part II addresses different approaches to radiation damage modelling. In Part III biomedical aspects of radiation effects are treated on different scales. After the physics-oriented focus of the previous parts, there is a gradual transition to biology and medicine with the increasing size of the object studied. Finally, Part IV is dedicated to current trends and novel techniques in radiation reserach and the applications hence arising. It includes new developments in radiotherapy and related cancer therapies, as well as technical optimizations of accelerators and totally new equipment designs, giving a glimpse of the near future of radiation-based medical treatments.

Table of contents (30 chapters)

Table of contents (30 chapters)
  • Nanoscale Dynamics of Radiosensitivity: Role of Low Energy Electrons

    Pages 3-43

    Sanche, Léon

  • The Role of Secondary Electrons in Radiation Damage

    Pages 45-58

    Denifl, Stephan (et al.)

  • Electron Transfer-Induced Fragmentation in (Bio)Molecules by Atom-Molecule Collisions

    Pages 59-70

    Limão-Vieira, Paulo (et al.)

  • Following Resonant Compound States after Electron Attachment

    Pages 71-86

    Sanz, Ana G. (et al.)

  • Electron–Biomolecule Collision Studies Using the Schwinger Multichannel Method

    Pages 87-113

    Winstead, Carl (et al.)

Buy this book

eBook $119.00
price for Mexico (gross)
  • ISBN 978-94-007-2564-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for Mexico
  • ISBN 978-94-007-2563-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for Mexico
  • ISBN 978-94-007-9582-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the eBook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Radiation Damage in Biomolecular Systems
Editors
  • Gustavo García Gómez-Tejedor
  • Martina Christina Fuss
Series Title
Biological and Medical Physics, Biomedical Engineering
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Canopus Academic Publishing Limited
eBook ISBN
978-94-007-2564-5
DOI
10.1007/978-94-007-2564-5
Hardcover ISBN
978-94-007-2563-8
Softcover ISBN
978-94-007-9582-2
Series ISSN
1618-7210
Edition Number
1
Number of Pages
XIV, 510
Topics