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Etiology and Morphogenesis of Congenital Heart Disease

From Gene Function and Cellular Interaction to Morphology

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  • Open Access
  • © 2016

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Overview

  • Focuses on the etiology and morphogenesis of congenital heart disease
  • Includes contributions by an international group of distinguished scientists and clinicians
  • Highlights the latest research topics and techniques and includes chapters dedicated to clinical implications and future directions
  • Includes supplementary material: sn.pub/extras

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Table of contents (55 chapters)

  1. From Molecular Mechanism to Intervention for Congenital Heart Diseases, Now and the Future

  2. Left-Right Axis and Heterotaxy Syndrome

  3. Cardiomyocyte and Myocardial Development

Keywords

About this book

This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration.   This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.


Editors and Affiliations

  • Department of Pediatric Cardiology, Tokyo Women's Medical University, Tokyo, Japan

    Toshio Nakanishi

  • Cardiovascular Developmental Biology Center, Medical University of South Carolina Clemson University, Charleston, USA

    Roger R. Markwald

  • Department of Pediatrics (Cardiology), Vanderbilt University, Nashville, USA

    H.Scott Baldwin

  • Pediatrics, Pharmacology and Toxicology, and Bioengineering, University of Louisville, Louisville, USA

    Bradley B. Keller

  • Gladstone Institute of Cardiovascular Disease, San Francisco, USA

    Deepak Srivastava

  • Pediatrics, Division of Pediatric Cardiology, Keio University School of Medicine, Tokyo, Japan

    Hiroyuki Yamagishi

Bibliographic Information

  • Book Title: Etiology and Morphogenesis of Congenital Heart Disease

  • Book Subtitle: From Gene Function and Cellular Interaction to Morphology

  • Editors: Toshio Nakanishi, Roger R. Markwald, H.Scott Baldwin, Bradley B. Keller, Deepak Srivastava, Hiroyuki Yamagishi

  • DOI: https://doi.org/10.1007/978-4-431-54628-3

  • Publisher: Springer Tokyo

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and the Author(s) 2016

  • Hardcover ISBN: 978-4-431-54627-6Published: 05 July 2016

  • Softcover ISBN: 978-4-431-56633-5Published: 07 June 2018

  • eBook ISBN: 978-4-431-54628-3Published: 24 June 2016

  • Edition Number: 1

  • Number of Pages: XII, 383

  • Number of Illustrations: 14 b/w illustrations, 95 illustrations in colour

  • Topics: Cardiology, Pediatric Surgery, Embryology, Pediatrics

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