Antiphospholipid Syndrome
Current Research Highlights and Clinical Insights
Editors: Erkan, Doruk, Lockshin, Michael D. (Eds.)
Free Preview- A comprehensive and thorough collection of essays on all aspects of APS by internationally recognized authorities in the field
- Presents the latest state-of-the-art information about evidence-based practice
- Describes new treatments and diagnostic tools and the significant developments in pathophysiology of APS
- Of interest to all clinicians involved in the treatment and management of APS patients
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- About this book
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This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.
- About the authors
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Doruk Erkan, MD, MPH, Associate Attending Physician, Associate Professor of Medicine, Department of Rheumatology, Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, USA, Michael D. Lockshin, MD, Attending Physician, Professor of Medicine and Obstetrics-Gynecology, Department of Rheumatology, Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, USA
- Table of contents (20 chapters)
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History of Antiphospholipid Antibody
Pages 3-11
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Natural Proteins Involved in Antiphospholipid Syndrome
Pages 15-27
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Origin of Antiphospholipid Antibodies
Pages 29-52
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Recent Advances in Understanding of the Genetics of Antiphospholipid Syndrome
Pages 53-75
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Mechanisms of Antiphospholipid Antibody-Mediated Thrombosis
Pages 77-116
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Table of contents (20 chapters)
- Download Preface 1 PDF (96.6 KB)
- Download Sample pages 1 PDF (498.3 KB)
- Download Table of contents PDF (1.4 MB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Antiphospholipid Syndrome
- Book Subtitle
- Current Research Highlights and Clinical Insights
- Editors
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- Doruk Erkan
- Michael D. Lockshin
- Copyright
- 2017
- Publisher
- Springer International Publishing
- Copyright Holder
- Springer International Publishing AG
- eBook ISBN
- 978-3-319-55442-6
- DOI
- 10.1007/978-3-319-55442-6
- Hardcover ISBN
- 978-3-319-55440-2
- Softcover ISBN
- 978-3-319-85662-9
- Edition Number
- 1
- Number of Pages
- XX, 372
- Number of Illustrations
- 2 b/w illustrations, 16 illustrations in colour
- Topics
