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Biochemistry of Oxidative Stress

Physiopathology and Clinical Aspects

  • Book
  • © 2016

Overview

Editors:
  1. Ricardo Jorge Gelpi

    1. School of Medicine, University of Buenos Aires, Buenos Aires, Argentina

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  2. Alberto Boveris

    1. School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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  3. Juan José Poderoso

    1. Instituto de Inmunología, Genética y Metabolismo (INIGEM, UBA–CONICET), Laboratorio de Metabolismo del Oxígeno, Hospital Universitario, Universidad de Buenos Aires, Buenos Aires, Argentina

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  • Covers all aspects of oxidative stress
  • Chapters submitted from leading researchers worldwide
  • Edited by an internationally recognized scientists
  • Covers the complete spectrum in oxidative stress research from very basic aspects through to antioxidant therapy

Part of the book series: Advances in Biochemistry in Health and Disease (ABHD, volume 16)

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xi
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  2. General Aspects

    1. Front Matter

      Pages 1-1
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    2. The Concept of Oxidative Stress After 30 Years

      • Helmut Sies
      Pages 3-11

    3. The Evolution of the Earth and Its Atmosphere

      • Juan José Poderoso
      Pages 13-22

    4. Mitochondria Are the Main Cellular Source of O2 −, H2O2 and Oxidative Stress

      • Alberto Boveris, Marisa G. Repetto
      Pages 23-35

    5. Biochemistry and Physiology of Heart Mitochondrial Nitric Oxide Synthase

      • Tamara Zaobornyj, Darío E. Iglesias, Silvina S. Bombicino, Ivana A. Rukavina-Mikusic, Laura B. Valdez
      Pages 37-48

    6. Biochemistry of Nitric Oxide and Peroxynitrite: Sources, Targets and Biological Implications

      • Adrián Aicardo, Débora M. Martinez, Nicolás Campolo, Silvina Bartesaghi, Rafael Radi
      Pages 49-77

    7. Nitro-arachidonic Acid: Downstream Signaling and Therapeutics

      • Homero Rubbo, Lucía González-Perilli, Mauricio Mastrogiovanni, Beatriz Sánchez-Calvo, Andrés Trostchansky
      Pages 79-93

    8. Mitochondrial Transfer by Intercellular Nanotubes

      • Viviana Sanchez, Alicia Brusco
      Pages 95-108

    9. Human Adaptation to Life at High Altitude

      • Gustavo F. Gonzales, Dulce E. Alarcón-Yaquetto, Alisson Zevallos-Concha
      Pages 109-126

  3. Cardiovascular Diseases

    1. Front Matter

      Pages 127-127
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    2. Role of Oxidative Stress in Subcellular Defects in Ischemic Heart Disease

      • Monika Bartekova, Miroslav Barancik, Naranjan S. Dhalla
      Pages 129-146

    3. Reduced Oxidative Stress as a Mechanism for Increased Longevity, Exercise and Heart Failure Protection with Adenylyl Cyclase Type 5 Inhibition

      • Stephen F. Vatner, Jie Zhang, Dorothy E. Vatner
      Pages 147-161

    4. Regulation of Protein Nitrosylation by Thioredoxin 1

      • Narayani Nagarajan, Junichi Sadoshima
      Pages 163-175

    5. Thioredoxin Attenuates Post-ischemic Damage in Ventricular and Mitochondrial Function

      • Veronica D’Annunzio, Virginia Perez, Tamara Mazo, Ricardo Jorge Gelpi
      Pages 177-191

    6. Antioxidant Supplementation in Cardiovascular Disease and Hypertension

      • José Milei, Susana Vila, Francisco Azzato, Giuseppe Ambrosio, Matilde Otero-Losada
      Pages 193-212

    7. Oxidative Stress Influence in the Development of Pulmonary Arterial Hypertension

      • Adriane Belló-Klein, Alex Sander Araujo, Paulo Cavalheiro Schenkel, Bruna Gazzi de Lima Seolin
      Pages 213-226

    8. Redox Regulation of Vascular Remodeling

      • Leonardo Y. Tanaka, Denise de Castro Fernandes, Francisco R. M. Laurindo
      Pages 227-243

    9. Mitochondrial Complex I Inactivation After Ischemia-Reperfusion in the Stunned Heart

      • Laura B. Valdez, Silvina S. Bombicino, Darío E. Iglesias, Ivana A. Rukavina-Mikusic, Verónica D’Annunzio
      Pages 245-257

    10. Reactive Oxygen Species Are Involved in Myocardial Remote Ischemic Preconditioning

      • Martín Donato, Diamela T. Paez, Pablo Evelson, Ricardo Jorge Gelpi
      Pages 259-274
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Keywords

About this book

The strongest point of this book titled “Biochemistry of Oxidative Stress: Physiopathology and Clinical Aspects”, is that the academic and scientific background of the authors/editors guarantee the authorship of a book comprising all aspects of oxidative stress, ranging from very molecular aspects, to clinical application, including the antioxidant therapy. Of particular importance is the fact that the aforementioned aspects are described in the book in a general section and in three different and important pathologies, such as cardiovascular diseases, neurodegenerative diseases, and cancer. The importance of these pathologies lays in the fact that, taken separately or together, they represent by far the leading cause of death in the world. Finally, all the chapters have been written by highly recognized authorities in the field of their investigations. At least to our knowledge, this is the first book with this characteristics in the field of oxidative stress.



Editors and Affiliations

  • School of Medicine, University of Buenos Aires, Buenos Aires, Argentina

    Ricardo Jorge Gelpi

  • School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

    Alberto Boveris

  • Instituto de Inmunología, Genética y Metabolismo (INIGEM, UBA–CONICET), Laboratorio de Metabolismo del Oxígeno, Hospital Universitario, Universidad de Buenos Aires, Buenos Aires, Argentina

    Juan José Poderoso

Bibliographic Information

  • Book Title: Biochemistry of Oxidative Stress

  • Book Subtitle: Physiopathology and Clinical Aspects

  • Editors: Ricardo Jorge Gelpi, Alberto Boveris, Juan José Poderoso

  • Series Title: Advances in Biochemistry in Health and Disease

  • DOI: https://doi.org/10.1007/978-3-319-45865-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-45864-9Published: 05 January 2017

  • Softcover ISBN: 978-3-319-83388-0Published: 21 July 2018

  • eBook ISBN: 978-3-319-45865-6Published: 28 December 2016

  • Series ISSN: 2512-2142

  • Series E-ISSN: 2512-2150

  • Edition Number: 1

  • Number of Pages: XI, 454

  • Number of Illustrations: 27 b/w illustrations, 47 illustrations in colour

  • Topics: Cancer Research, Cell Physiology, Oxidative Stress

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