Pericyte Biology in Disease

1. Front Matter

   Pages i-xii

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2. Pericytes in Cutaneous Wound Healing

   • Shunichi Morikawa, Haizea Iribar, Araika Gutiérrez-Rivera, Taichi Ezaki, Ander Izeta

   Pages 1-63

3. Pericytes in Glioblastomas: Multifaceted Role Within Tumor Microenvironments and Potential for Therapeutic Interventions

   • Anirudh Sattiraju, Akiva Mintz

   Pages 65-91

4. Pericytes in Breast Cancer

   • Jiha Kim

   Pages 93-107

5. Pericytes in Sarcomas and Other Mesenchymal Tumors

   • Leslie Chang, Michelle A. Scott, Carolyn A. Meyers, Aaron W. James

   Pages 109-124

6. Pericytes in Metastasis

   • Zalitha Pieterse, Devbarna Sinha, Pritinder Kaur

   Pages 125-135

7. The Role of Pericytes in Amyotrophic Lateral Sclerosis

   • Giuliana Castello Coatti, Natale Cavaçana, Mayana Zatz

   Pages 137-146

8. Pericytes in Alzheimer’s Disease: Novel Clues to Cerebral Amyloid Angiopathy Pathogenesis

   • Alla B. Salmina, Yulia K. Komleva, Olga L. Lopatina, Alexander Birbrair

   Pages 147-166

9. Pericytes in Multiple Sclerosis

   • Francisco J. Rivera, Bryan Hinrichsen, Maria Elena Silva

   Pages 167-187

10. Pericytes in Ischemic Stroke

    • Turgay Dalkara, Luis Alarcon-Martinez, Muge Yemisci

    Pages 189-213

11. Pericytes in Hereditary Hemorrhagic Telangiectasia

    • Georgios Galaris, Jérémy H. Thalgott, Franck P. G. Lebrin

    Pages 215-246

12. Pericytes in Primary Familial Brain Calcification

    • Yvette Zarb, Francesca Daniela Franzoso, Annika Keller

    Pages 247-264

13. Pericytes in Type 2 Diabetes

    • Katherine L. Hayes

    Pages 265-278

14. Pericytes in Atherosclerosis

    • Volha Summerhill, Alexander Orekhov

    Pages 279-297

15. Pericytes in Chronic Lung Disease

    • Bushra Shammout, Jill R. Johnson

    Pages 299-317

16. Pericytes in Muscular Dystrophies

    • Louise Anne Moyle, Francesco Saverio Tedesco, Sara Benedetti

    Pages 319-344

17. Back Matter

    Pages 345-355

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This volume explores pericytes' roles under distinct pathological conditions, ranging from tumors, ALS, Alzheimer’s disease, Multiple Sclerosis, stroke, diabetes, atherosclerosis, muscular dystrophies and more. Together with its companion volumes Pericyte Biology in Different Organs and Pericyte Biology – Novel Concepts, Pericyte Biology in Disease presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cell biology and clinicians involved with these specific diseases.

• pericytes
• endothelial cells
• homeostasis
• stem cell biology
• disease regulation

• Department of Radiology, Columbia University Medical Center, New York, USA

  Alexander Birbrair

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

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