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  • Book
  • © 2013

Peptide Synthesis and Applications

  • Practical methodologies for peptide synthesis
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1047)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-x
  2. Linkers, Resins, and General Procedures for Solid-Phase Peptide Synthesis

    • Pernille Tofteng Shelton, Knud J. Jensen
    Pages 23-41
  3. Peptide Release, Side-Chain Deprotection, Work-Up, and Isolation

    • Søren L. Pedersen, Knud J. Jensen
    Pages 43-63
  4. Synthesis of Peptides Using Tert-Butyloxycarbonyl (Boc) as the α-Amino Protection Group

    • Søren W. Pedersen, Christopher J. Armishaw, Kristian Strømgaard
    Pages 65-80
  5. Sequential Formation of Regioselective Disulfide Bonds in Synthetic Peptides with Multiple Disulfide Bonds

    • Fazel Shabanpoor, Mohammed Akhter Hossain, Feng Lin, John D. Wade
    Pages 81-87
  6. Synthesis of Cyclic Disulfide-Rich Peptides

    • Muharrem Akcan, David J. Craik
    Pages 89-101
  7. Preparation of C-terminally Modified Chemokines by Expressed Protein Ligation

    • Lars Baumann, Max Steinhagen, Annette G. Beck-Sickinger
    Pages 103-118
  8. Synthesis of Antimicrobial Peptoids

    • Paul R. Hansen, Jens K. Munk
    Pages 151-159
  9. Synthesis of Lipidated Peptides

    • Federica Rosi, Gemma Triola
    Pages 161-189
  10. Solid-Phase Synthesis of Phosphopeptides

    • Kim B. Højlys-Larsen, Knud J. Jensen
    Pages 191-199
  11. Instruments for Automated Peptide Synthesis

    • Søren L. Pedersen, Knud J. Jensen
    Pages 215-224
  12. Back Matter

    Pages 251-253

About this book

Peptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging.  The second edition of  Peptide Synthesis and Applications expands upon the previous editions with current, detailed methodologies for peptide synthesis. With new chapters on laboratory protocols for both the specialist and the non-specialist. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical, Peptide Synthesis and Application, Second Edition seeks to aid scientists in understanding different approaches to the synthesis of peptides by using a broad range of methods and strategies.

Editors and Affiliations

  • IGM, Faculty of Sciences, University of Copenhagen, Frederiksberg, Denmark

    Knud J. Jensen

  • IGM, Faculty of Science, University of Copenhagen, Glostrup, Denmark

    Pernille Tofteng Shelton

  • IGM, Faculty of Life Sciences, University of Copenhagen, Hørsholm, Denmark

    Søren L. Pedersen

Bibliographic Information

  • Book Title: Peptide Synthesis and Applications

  • Editors: Knud J. Jensen, Pernille Tofteng Shelton, Søren L. Pedersen

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-62703-544-6

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, New York 2013

  • Hardcover ISBN: 978-1-62703-543-9Published: 14 August 2013

  • Softcover ISBN: 978-1-4939-6004-0Published: 27 August 2016

  • eBook ISBN: 978-1-62703-544-6Published: 15 August 2013

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: X, 253

  • Number of Illustrations: 68 b/w illustrations

  • Topics: Biochemistry, general

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access