Gestational Trophoblastic Disease
Diagnostic and Molecular Genetic Pathology
Editors: Hui, Pei (Ed.)
Free Preview- Comprehensive presentation of histological diagnosis and differential diagnoses of GTD
- In-depth reviews of the molecular genetic background of GTD, epidemiology and risk factors
- Updates of current therapeutic options for GTD
- In-depth discussions of applications of molecular genetic pathology in GTD
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- About this book
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In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations.
Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent advances in our understanding of the genetics of gestational trophoblastic diseases are stressed. Introductory chapters cover the developmental biology of the placenta and the genetic basis of gestational trophoblastic disease, and one chapter is devoted to the molecular diagnosis of gestational trophoblastic disease. This chapter includes a review of the use of short tandem repeat (STR) genotyping which is of particular value in the diagnosis of hydatidiform moles. The final chapter covers clinical aspects of gestational trophoblastic disease, including treatment. The text throughout is current and thoroughly referenced. This book will be of great value to pathologists, community gynecologists, gynecological pathologists and medical students.
- Reviews
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From the reviews:
“The book has 12 chapters, each documented by approximately 100 references. … As many of the basic facts are repeated in most chapters, the book is best as a reference book. … Pei Hui has, with great effort, collected and updated knowledge within the field of trophoblastic disease. Overall, the book is well written, covering all aspects and presenting many well-made illustrations. The book serves as a useful handbook, mainly for pathologists with a special interest in trophoblastic disease.” (Isa Niemann, Acta Obstetricia et Gynecologica Scandinavica, Vol. 91 (9), September, 2012)
- Table of contents (12 chapters)
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Gestational Trophoblastic Disease: General Aspects
Pages 1-14
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Developmental Biology of the Placenta
Pages 15-39
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Genetic Basis of Gestational Trophoblastic Disease
Pages 41-55
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Complete Hydatidiform Mole
Pages 57-75
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Partial Hydatidiform Mole
Pages 77-90
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Table of contents (12 chapters)
- Download Preface 1 PDF (158.5 KB)
- Download Sample pages 1 PDF (2.4 MB)
- Download Table of contents PDF (172.7 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Gestational Trophoblastic Disease
- Book Subtitle
- Diagnostic and Molecular Genetic Pathology
- Editors
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- Pei Hui
- Series Title
- Current Clinical Pathology
- Copyright
- 2012
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media, LLC
- eBook ISBN
- 978-1-61779-394-3
- DOI
- 10.1007/978-1-61779-394-3
- Hardcover ISBN
- 978-1-61779-393-6
- Softcover ISBN
- 978-1-4939-5924-2
- Series ISSN
- 2197-781X
- Edition Number
- 1
- Number of Pages
- XIII, 205
- Topics
