Methods in Molecular Biology

Apoptosis and Cancer

Methods and Protocols

Editors: Mor, Gil, Alvero, Ayesha (Eds.)

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  • Readily reproducible, cutting-edge techniques for studying the biology of apoptosis
  • Step-by-step instructions that ensure successful results
  • Tricks of the trade and notes on troubleshooting and avoiding known pitfalls
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eBook $109.00
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  • ISBN 978-1-59745-339-4
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Hardcover $219.99
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  • ISBN 978-1-58829-457-9
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Softcover $149.00
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  • ISBN 978-1-61737-582-8
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  • Usually dispatched within 3 to 5 business days.
About this book

Our understanding of the apoptotic pathway and its regulation has improved significantly in the last 10 years. However, as our knowledge of the intricate intracellular events increase, we realize the complexity of the regulatory mechanisms that control it. As such, Apoptosis and Cancer describes the performance of contemporary techniques for studying the biology of apoptosis and its role in cancer. This book is a collaboration between academics- and industry-based scientists. The chapters have the technical development characteristic of an academic environment and the standardized system necessary for translating a product to general use, as provided by the industry. Thus, the protocols described within this groundbreaking new volume will aid both an academic laboratory interested in further characterizing the mechanism of apoptosis and an industry laboratory interested on identifying new target molecules or screening for new compounds with potential clinical use. The authors – all leaders in the field – have created a comprehensive text that covers the newest available techniques as well as conventional basic techniques. Apoptosis and Cancer will undoubtedly provide the necessary resources to everyone interested in the area of apoptosis.

Reviews

From the reviews:

"Divided among 17 chapters, the condensed information about apoptosis, its pathways and the performance of progressive techniques for apoptosis assessment are presented. … The valuable and most appreciated part of each chapter are notes – the reader will find here the plethora of hints, the real grain of wisdom, virtual wizard that saves a lot of struggling time at benchtop. This book belongs to the category of must-have books." (J. Sedlák, Neoplasma, September, 2008)


Table of contents (17 chapters)

Table of contents (17 chapters)
  • Modulation of Apoptosis to Reverse Chemoresistance

    Pages 1-12

    Mor, Gil (et al.)

  • Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis

    Pages 13-21

    Mazumder, Suparna (et al.)

  • Flow Cytometry Enumeration of Apoptotic Cancer Cells by Apoptotic Rate

    Pages 23-33

    Diaz, David (et al.)

  • Detection of Cancer-Related Proteins in Fresh-Frozen Ovarian Cancer Samples Using Laser Capture Microdissection

    Pages 35-45

    Silasi, Dan-Arin (et al.)

  • Flow Cytometric Detection of Activated Caspase-3

    Pages 47-56

    Fox, Richard (et al.)

Buy this book

eBook $109.00
price for Mexico (gross)
  • ISBN 978-1-59745-339-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for Mexico
  • ISBN 978-1-58829-457-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $149.00
price for Mexico
  • ISBN 978-1-61737-582-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Apoptosis and Cancer
Book Subtitle
Methods and Protocols
Editors
  • Gil Mor
  • Ayesha Alvero
Series Title
Methods in Molecular Biology
Series Volume
414
Copyright
2008
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-339-4
DOI
10.1007/978-1-59745-339-4
Hardcover ISBN
978-1-58829-457-9
Softcover ISBN
978-1-61737-582-8
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 266
Number of Illustrations
69 b/w illustrations
Topics