Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1731)
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Table of contents (27 protocols)
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Front Matter
About this book
This volume explores the role of proteases in various catalytic classes and cellular processes associated with cancer. The chapters in this book cover topics such as encoding proteolytic enzymes, cleavage sites of proteases, functional catalytic domains of MMPs, zymography, angiogenesis and lymphangiogenesis, genetic and epigenetic alterations of metallopeptidases, and methods to target metalloproteinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting edge, Proteases and Cancer: Methods and Protocols is a valuable resource for clinical researchers across numerous fields such as molecular and cellular biology, oncology, biochemistry, and chemistry. This book is also useful for PhD students in the various disciples of health sciences.
Editors and Affiliations
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Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain
Santiago Cal, Alvaro J. Obaya
Bibliographic Information
Book Title: Proteases and Cancer
Book Subtitle: Methods and Protocols
Editors: Santiago Cal, Alvaro J. Obaya
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7595-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2018
Hardcover ISBN: 978-1-4939-7594-5Published: 10 January 2018
Softcover ISBN: 978-1-4939-8531-9Published: 04 June 2019
eBook ISBN: 978-1-4939-7595-2Published: 09 January 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 352
Number of Illustrations: 17 b/w illustrations, 41 illustrations in colour
Topics: Cancer Research