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Self-Assembling Peptide Systems in Biology, Medicine and Engineering

Editors: Aggeli, A., Boden, N., Shuguang, Zhang (Eds.)

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eBook $189.00
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  • ISBN 978-0-306-46890-2
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Hardcover $249.99
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  • ISBN 978-0-7923-7090-1
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Softcover $249.99
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  • ISBN 978-90-481-5740-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

One ofthe major drivers in biological research is the establishment ofstructures and functions of the 50,000 or so proteins in our bodies. Each has a characteristic- dimensional structure, highly "ordered" yet "disordered"! This structure is essential for a protein's function and, significantly, it must be sustained in the competitive and complex environment of the living cell. It is now being recognised that when a cell loses control, proteins can se- assemble into more complex supermolecular structures such as the amyloid fibres and plaques associated with the pathogenesis of prion (CJD) or age-related (Alzheimer's) diseases. This is a pointer to the wider significance of the self-assembling properties of polypeptides. It has been long known that, in silk, polypeptides are assembled into- sheet structures which impart on the material its highly exploitable properties of flexibility combined with high tensile strength. But only now emerging is the recognition that peptides can Self-assemble into a wide variety of non-protein-like structures, including fibrils, fibres, tubules, sheets and monolayers. These are exciting observations and, more so, the potential for materials and medical exploitations is so wide ranging that over 80 scientists from Europe, USA, Japan and Israel. met 1-6 July 1999 in Crete, to discuss the wide-ranging implications of these novel developments. There was a spirit of excitement about the workshop indicative of an important new endeavor. The emerging perception is that of a new class of materials set to become commercially viable early in the 21st century.

Table of contents (24 chapters)

  • Exploiting Peptide Self-assembly to Engineer Novel Biopolymers: Tapes, Ribbons, Fibrils and Fibres

    Aggeli, A. (et al.)

    Pages 1-17

  • Ribbon-Like Lamellar Structures from Chain-Folded Polypeptides

    Atkins, E. D. T.

    Pages 19-33

  • Design of Self-Assembling Peptides as Catalyst Mimetics Using Synthetic Combinatorial Libraries

    Blondelle, S. E. (et al.)

    Pages 35-45

  • Thermodynamics of Protein-Protein and Peptide Interactions

    Cooper, Alan

    Pages 47-64

  • The Mechanism of Amyloid Formation and Its Links to Human Disease and Biological Evolution

    Dobson, Christopher M.

    Pages 65-74

Buy this book

eBook $189.00
price for Mexico (gross)
  • ISBN 978-0-306-46890-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for Mexico
  • ISBN 978-0-7923-7090-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for Mexico
  • ISBN 978-90-481-5740-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Self-Assembling Peptide Systems in Biology, Medicine and Engineering
Editors
  • A. Aggeli
  • N. Boden
  • Zhang Shuguang
Copyright
2002
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-0-306-46890-2
DOI
10.1007/0-306-46890-5
Hardcover ISBN
978-0-7923-7090-1
Softcover ISBN
978-90-481-5740-2
Edition Number
1
Number of Pages
XII, 364
Topics