Overview
- Comprehensive coverage of pathogenesis, diagnosis, available treatments, drug safety, regenerative and precision medicine in osteoarthritis
- Contributions from leading osteoarthritis researchers, clinicians and surgeons
- Easy to read and comprehend, the book not only addresses scientists, clinicians and students, but also people with osteoarthritis or related joint disease
- Includes supplementary material: sn.pub/extras
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About this book
This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patient’s phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics.
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Keywords
Table of contents (13 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
About the editors
Dr. Mohit Kapoor is an Associate Professor in the Department of Surgery and the Department of Laboratory Medicine and Pathobiology at the University of Toronto, Canada. He heads the cartilage biology research group within the Arthritis Program at the Toronto Western Research Institute, University Health Network, Toronto. His research program is directed towards understanding the complex pathophysiology of OA and identifying new therapeutic strategies to counteract the destruction of articular cartilage during OA. Specifically, his research is focused towards (a) understanding the mechanisms that are essential for maintaining articular cartilage homeostasis and mechanisms that trigger cell death and articular cartilage damage, and (b) identifying new OA biomarkers. Dr. Kapoor has published over 50 research articles, reviews and book chapters and is a recipient of several prestigious research awards.
Dr. Nizar Mahomed is head of the Division of Orthopaedic Surgery at the University Health Network and Professor in the Department of Surgery at the University of Toronto, Canada. He is Nicki and Bryce Douglas Chair and Smith & Nephew Chair in Orthopaedic Surgery. Clinically he focuses on complex primary and revision hip and knee replacement surgery. He has over 100 publications and book chapters. His research interests are in the areas of health systems research focusing on models of care for orthopaedic conditions and translational research looking at regenerative options for OA. Dr. Mahomed has received several awards for his research and is the recipient of the first CIHR-CMAJ Top Canadian Achievements in Health Research Award. As Medical Director of the Arthritis Program at University Health Network, he leads the largest integrated Arthritis Program in Canada.
Bibliographic Information
Book Title: Osteoarthritis
Book Subtitle: Pathogenesis, Diagnosis, Available Treatments, Drug Safety, Regenerative and Precision Medicine
Editors: Mohit Kapoor, Nizar N. Mahomed
DOI: https://doi.org/10.1007/978-3-319-19560-5
Publisher: Adis Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-19559-9Published: 23 July 2015
Softcover ISBN: 978-3-319-36265-6Published: 15 October 2016
eBook ISBN: 978-3-319-19560-5Published: 20 July 2015
Edition Number: 1
Number of Pages: X, 278
Number of Illustrations: 20 b/w illustrations, 10 illustrations in colour