Overview
This book provides commonly used techniques with Drosophila eye model so that readers can easily understand the following sections
The chapters are organized in a way that it has characters of both review and handbook
The book will emphasize the use of Drosophila model to study eye development and use of Drosophila eye to study human disease
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Table of contents (12 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Drosophila melanogaster (fruit fly) is a highly versatile model with a genetic legacy of more than a century. It provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases. One of the most important questions in biology is how a multi-cellular organism develops from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question and has led to other questions, such as the role of various genetic and cell biological pathways in regulating the process of pattern formation and growth during organogenesis. The Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa.
This updated second edition covers current progress in the study of molecular genetic mechanisms of pattern formation, mutations in axial patterning, genetic regulation of growth, and more using the Drosophila eye as a model.Editors and Affiliations
About the editors
Dr. Madhuri Kango-Singh, is a tenured Associate Professor in the Department of Biology at University of Dayton (OH). Dr. Kango-Singh works in the area of growth regulation and cancer using genetic approaches in Drosophila. Dr. Kango-Singh completed her Ph.D. in growth regulation in Drosophila from D.A. University Indore (India). Between 1997-2002 Dr. Kango-Singh pursued postdoctoral research at Indian Institute of Science, Bangalore (India) and Academia Sinica, Taiwan in the areas of silkworm and Drosophila development. In 2002, Dr. Kango-Singh joined The University of Texas M D Anderson Cancer Center as a postdoctoral fellow and later as an Instructor to work on growth regulatory pathways in Drosophila where she played a key role in the identification of key components of the Hippo pathway. In 2007 Dr. Kango-Singh joined the Basic Sciences Division at Mercer University School of Medicine as a Tenure-Track Assistant Professor. In 2009, Dr. Kango-Singh moved as an Assistant Professor (Tenure-track) to the University of Dayton where she was promoted to Associate Professor with Tenure in 2015.
Bibliographic Information
Book Title: Molecular Genetics of Axial Patterning, Growth and Disease in Drosophila Eye
Editors: Amit Singh, Madhuri Kango-Singh
DOI: https://doi.org/10.1007/978-3-030-42246-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-42245-5Published: 19 May 2020
Softcover ISBN: 978-3-030-42248-6Published: 19 May 2021
eBook ISBN: 978-3-030-42246-2Published: 18 May 2020
Edition Number: 2
Number of Pages: XIV, 368
Number of Illustrations: 8 b/w illustrations, 73 illustrations in colour
Topics: Human Genetics, Animal Models, Animal Genetics and Genomics