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Handbook of Experimental Pharmacology

Calcitonin Gene-Related Peptide (CGRP) Mechanisms

Focus on Migraine

Editors: Brain, Susan, Geppetti, Pierangelo (Eds.)

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  • Provides a thorough review of the key recent research into the role of CGRP in health and disease
  • Enables and enriches understanding of CGRP in migraine pathophysiology
  • Provides a full update of the latest therapeutic perspectives and clinical advancements with potential therapeutic agents that block the actions of CGRP
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eBook 83,29 €
price for Korea, Republic of (South Korea) (gross)
  • ISBN 978-3-030-21454-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 129,99 €
price for Korea, Republic of (South Korea) (gross)
  • 까지: September 27, 2019
  • ISBN 978-3-030-21453-1
  • Free shipping for individuals worldwide
About this book

This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine.  The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention. 

Table of contents (11 chapters)

Table of contents (11 chapters)

Buy this book

eBook 83,29 €
price for Korea, Republic of (South Korea) (gross)
  • ISBN 978-3-030-21454-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 129,99 €
price for Korea, Republic of (South Korea) (gross)
  • 까지: September 27, 2019
  • ISBN 978-3-030-21453-1
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Calcitonin Gene-Related Peptide (CGRP) Mechanisms
Book Subtitle
Focus on Migraine
Editors
  • Susan Brain
  • Pierangelo Geppetti
Series Title
Handbook of Experimental Pharmacology
Series Volume
255
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-21454-8
DOI
10.1007/978-3-030-21454-8
Hardcover ISBN
978-3-030-21453-1
Series ISSN
0171-2004
Edition Number
1
Number of Pages
VII, 192
Number of Illustrations
6 b/w illustrations, 17 illustrations in colour
Topics