Surface Modification of Nanoparticles for Targeted Drug Delivery

1. Front Matter

   Pages i-xviii

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2. Understanding Surface Characteristics of Nanoparticles

   • Ashley Oake, Priyanka Bhatt, Yashwant V Pathak

   Pages 1-17

3. Surface Modification of Nanoparticles for Targeted Drug Delivery

   • Param Patel, Anas Hanini, Achal Shah, Dhruv Patel, Shyam Patel, Priyanka Bhatt et al.

   Pages 19-31

4. Surface-Modified PLGA Nanoparticles for Targeted Drug Delivery to Neurons

   • Tejal A. Mehta, Neha Shah, Khushali Parekh, Namdev Dhas, Jayvadan K. Patel

   Pages 33-71

5. Surface-Functionalized Lipid Nanoparticles for Site-Specific Drug Delivery

   • Diana P. Gaspar, António J. Almeida

   Pages 73-98

6. Stealth Properties of Nanoparticles Against Cancer: Surface Modification of NPs for Passive Targeting to Human Cancer Tissue in Zebrafish Embryos

   • Samson A. Adeyemi, Pradeep Kumar, Yahya E. Choonara, Viness Pillay

   Pages 99-124

7. Passive Targeting of Nanoparticles to Cancer

   • Jayvadan K. Patel, Anita P. Patel

   Pages 125-143

8. Surface Modification of Magnetic Nanoparticles in Biomedicine

   • Viroj Wiwanitkit

   Pages 145-153

9. A Novel Strategy for the Surface Modification of Superparamagnetic (Fe3O4) Iron Oxide Nanoparticle for Lung Cancer Imaging

   • Mayank Bhushan, Yogesh Kumar

   Pages 155-165

10. Biodegradable Nanoparticles for Drug Delivery and Targeting

    • Viroj Wiwanitkit

    Pages 167-181

11. Functionalized Antibacterial Nanoparticles for Controlling Biofilm and Intracellular Infections

    • Aparna Viswanathan, Jayakumar Rangasamy, Raja Biswas

    Pages 183-206

12. Surface Modifications of Liposomes for Drug Targeting

    • Doniya Milani, Umi Athiyah, Dewi Melani Hariyadi, Yashwant V Pathak

    Pages 207-220

13. Surface Modification of Nanoparticles to Oppose Uptake by the Mononuclear Phagocyte System

    • Komal Parmar, Jayvadan K. Patel

    Pages 221-236

14. Surface Modification of Metallic Nanoparticles

    • Vignesh Nagarajan, Tafadzwa Justin Chiome, Sanjay Sudan

    Pages 237-244

15. Successful Delivery of Zidovudine-Loaded Docosanol Nanostructured Lipid Carriers (Docosanol NLCs) into Rat Brain

    • Tapash Chakraborty, Malay K. Das, Lopamudra Dutta, Biswajit Mukherjee, Sanjoy Das, Anupam Sarma

    Pages 245-276

16. Brain-Targeted Drug Delivery with Surface-Modified Nanoparticles

    • Sunita Lahkar, Malay K. Das

    Pages 277-310

17. Surface Modification of Resorcinarene-Based Self-Assembled Solid Lipid Nanoparticles for Drug Targeting

    • Sanjoy Das, Malay K. Das

    Pages 311-329

18. Targeted Delivery of Surface-Modified Nanoparticles: Modulation of Inflammation for Acute Lung Injury

    • Hiep X. Nguyen

    Pages 331-353

19. Surface Modification of Nanocarriers for Specific Cell Targeting for Better Therapeutic Effect

    • Doniya Milani, Umi Athiyah, Dewi Melani Hariyadi, Yashwant V Pathak

    Pages 355-368

20. Polydopamine-Based Simple and Versatile Surface Modification of Polymeric Nano Drug Carriers

    • Malay K. Das, Anupam Sarma, Trinayan Deka

    Pages 369-389

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

• nanotechnology
• drug delivery systems
• drug efficacy
• organelle targeting
• PLGA nanoparticles
• biointegrated block polymers
• nanodrug carriers
• brain targeted drug delivery
• anticancer drug delivery
• biodegradable nanoparticles
• cytoplasmic drug delivery
• magnetic nanoparticles
• iron oxide nanoparticles

• College of Pharmacy, University of South Florida, Tampa, USA

  Yashwant V Pathak

Prof. Yashwant Pathak, M.S., Ph.D. in Pharmaceutical Technology from Nagpur University, India and EMBA and MS in Conflict Management from Sullivan University, KY, USA. He is the Associate Dean for Faculty Affairs at the College of Pharmacy, University of South Florida. Tampa, Florida. With extensive experience in academia as well as industry, he has to his credit more than 100 publications and 2 patents, including 5 books in Nanotechnology and 2 in Nutraceuticals and several books in cultural studies. He is also the Coordinator for the International Center for Cultural Studies, and is on the board of many organizations.

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