Evidence Based Validation of Traditional Medicines

1. Front Matter

   Pages i-xii

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2. Phytomolecules, Drug Discovery and Modern Technique

   1. Front Matter

      Pages 1-1

      PDF

   2. Global Approach for Drug Discovery and Development from Indian Traditional Medicine

      • Shanti Bhushan Mishra, Alok Mukerjee, Shradhanjali Singh

      Pages 3-27

   3. Bioactive Natural Leads Targeting Cancer Cell Metabolism

      • Prasanta Dey, Amit Kundu, Babli Kar, Anushree Bhakta, Vineet Vishal, S. Keerthana et al.

      Pages 29-75

   4. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products

      • Madeleine Fleming, G. David Lin, Rachel W. Li

      Pages 77-96

   5. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects

      • Rachel W. Li, Partha Palit, Paul N. Smith, G. David Lin

      Pages 97-116

   6. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin

      • Naibedya Dutta, Suvranil Ghosh, Mahadeb Pal

      Pages 117-127

   7. Role of Phytomolecules on the Basic Biology of Aging

      • Swapnil Pandey, Puneet Singh Chauhan

      Pages 129-139

   8. Role of Phytomedicine in Alleviating Oxidative Stress-Mediated Vascular Complications in Diabetes

      • Rakhi Chakraborty, Vivekananda Mandal

      Pages 141-162

   9. Plant-Based β-Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer’s Disorder

      • Atanu Bhattacharjee, Raja Chakraborty, Saikat Sen

      Pages 163-175

   10. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis: Play a Pivotal Role in Combating Human Pathogens

       • Sunayana Saha, Soumaryya Bhattacharyya, Mausumi Sikdar (nee Bhakta), Rabindranath Bhattachryya

       Pages 177-194

   11. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development

       • Laxmi Rathor

       Pages 195-209

   12. Cell-Based Assays in Natural Product-Based Drug Discovery

       • Alka Mukne, Misbah Momin, Parag Betkar, Tanvi Rane, Saurabh Valecha

       Pages 211-248

   13. Allelochemicals: An Emerging Tool for Weed Management

       • Chandan Das, Avishek Dey, Abhijit Bandyopadhyay

       Pages 249-259

   14. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing

       • Somenath Das, Vipin Kumar Singh, Neha Upadhyay, Bijendra Kumar Singh, Jitendra Prasad, Shikha Tiwari et al.

       Pages 261-277

   15. Importance of Chromatography Techniques in Phytomedicine Research

       • Aditi Gujrati, Sourabh Jain, Veenu Joshi, Shiv Shankar Shukla, Amber Vyas, Vikas Jain

       Pages 279-297

   16. Reverse Pharmacology: A Tool for Drug Discovery from Traditional Medicine

       • V. Suba

       Pages 299-310

3. Standardization and Validation of Traditional Medicine and Medicinal Plant

   1. Front Matter

      Pages 311-311

      PDF

   2. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations

      • Koel Sinha, Sutapa Som Chaudhury, Bhuban Ruidas, Rabindranath Majumder, Tania Pal, Tapas K. Sur et al.

      Pages 313-336

   3. HPTLC Fingerprinting Analysis of Phytoconstituents from Indigenous Medicinal Plants

      • Shradhanjali Singh, Shanti Bhushan Mishra, Alok Mukerjee

      Pages 337-358

The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine.

• Quality Control
• Validation
• Traditional medicine
• Drug Discovery
• Toxicology
• Standardization
• antibacterial drug resistance

• Pharmaceutical Technology, Jadavpur University, Kolkata, India

  Subhash C. Mandal

• NEF College of Pharmacy, Guwahati, India

  Raja Chakraborty

• Faculty of Pharmaceutical Science, Assam down town University, Guwahati, India

  Saikat Sen

Prof. (Dr.) Subhash C Mandal is currently working as a Professor at Division of Pharmacognosy, Department of Pharmaceutical Technology, Jadavpur University, Kolkata India since 1997. His research achievements have been duly honored by many international organizations for awards. He has guided more than 30 PhD scholars and 25 M Pharm scholars and has completed 12 government-funded research projects on Indian Traditional Medicines and Drug Discovery. Prof. Mandal has more than 300 research publications (Citations: 14446, h-index : 59, i10-index : 322), 08 patents and several authored, edited and book chapters to his credit. He has visited more than 30 countries for various scientific deliberations, collaborations exchange programmes.

Dr. Raja Chakraborty is presently designated as Professor and Principal at NEF College of Pharmacy, Guwahati, Assam, India. He received his PhD in Pharmaceutical Sciences from Jawaharlal Nehru Technological University Anantapur, Indiain 2014. With 12 years of academic and research experience, he has published more than 60 research and review articles in reputed national and international journals. He authored two books “Tribal Medicinal Plants of Tripura, India: A scientific Search, Serial Publications, New Delhi and Diabetes Mellitus in 21st Century. Springer Singapore. He acted as editor for two books and nineteen book chapters with different national and international publishers. Recently he received “Dr. APJ Abdul Kalam Award for Teaching Excellence – 2018” He is guiding a number of Ph.D students and serving as Co-PI in a DBT-funded mega-project. 

Dr. Saikat Sen is an educationist and researcher, presently working as a professor at the Faculty of Pharmaceutical Sciences at Assam down town University, Guwahati. He has authored, and edited, various books and contributed chapters in different peer-reviewed edited books published by international/national publishers. More than 60 researchand review articles in peer-reviewed reputed national/international journals were added to his credit, presented several scientific papers, attended a number of national and international conferences, and delivered invitee lectures in international forums. He has received several awards during his 12 years of his professional carrier which include Sushruta Best Young Scientist Award, Dr. APJ Abdul Kalam Award for Young Scientists – 2018. He is a member of different professional bodies around the world and involve enthusiastically in scientific research on traditional/folk medicinal systems and to develop active research culture. 

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