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Advances in Experimental Medicine and Biology

Therapeutic Enzymes: Function and Clinical Implications

Editors: Labrou, Nikolaos (Ed.)

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  • Incorporates a wealth of research that clarifies several aspects of the development and application of therapeutic enzymes
  • Equips readers with a comprehensive understanding of enzyme-based therapeutic molecules
  • Emphasizes three areas of recombinant therapeutic enzymes and their clinical and pharmaceutical technology
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イーブック ¥15,724
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • ISBN 978-981-13-7709-9
  • ウォーターマーク付、 DRMフリー
  • ファイル形式: EPUB, PDF
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ハードカバー ¥28,079
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • 予定日: October 12, 2019
  • ISBN 978-981-13-7708-2
  • 個人のお客様には、世界中どこでも配送料無料でお届けします。
この書籍について

Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.

Table of contents (15 chapters)

Table of contents (15 chapters)

書籍の購入

イーブック ¥15,724
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • ISBN 978-981-13-7709-9
  • ウォーターマーク付、 DRMフリー
  • ファイル形式: EPUB, PDF
  • どの電子書籍リーダーからでもすぐにお読みいただけます。
  • ご購入後、すぐにダウンロードしていただけます。
ハードカバー ¥28,079
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • 予定日: October 12, 2019
  • ISBN 978-981-13-7708-2
  • 個人のお客様には、世界中どこでも配送料無料でお届けします。
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書誌情報

Bibliographic Information
Book Title
Therapeutic Enzymes: Function and Clinical Implications
Editors
  • Nikolaos Labrou
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1148
Copyright
2019
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
イーブック ISBN
978-981-13-7709-9
DOI
10.1007/978-981-13-7709-9
ハードカバー ISBN
978-981-13-7708-2
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 386
Number of Illustrations
19 b/w illustrations, 71 illustrations in colour
Topics