Springer Theses

New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules

Authors: Di Iorio, Nicola

  • ​Nominated as an outstanding Ph.D. thesis by the University of Bologna, Italy
  • Offers a comprehensive introduction on the general aspects of chirality and organocatalysis
  • Explores both vinylogy and atropisomerism
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eBook 91,62 €
price for Spain (gross)
  • ISBN 978-3-319-74914-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 114,39 €
price for Spain (gross)
  • ISBN 978-3-319-74913-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This thesis discusses the use of asymmetric organic catalysis for the direct enantioselective synthesis of complex chiral molecules, and by addressing the many aspects of both vinylogy and atropisomerism, it appeals to researchers and scholars interested in both areas.

Organocatalysis is a relatively modern and “hot” topic in the chemical community; it is constantly expanding and its use has been extended to interesting areas like vinylogous reactivity and atropisomerism. Vinylogous systems are very important for their synthetic applications but also pose a number of challenges, the most notable of which are their reduced reactivity and the reduced stereocontrol at these positions. On the other hand, atropisomeric systems are even more important because of the huge potential they have as drugs, ligands and catalysts. Chemists have only recently “recognized” the importance of these two areas and are focusing their efforts on studying them and the challenges they pose.

This thesis offers an extensive introduction on the general aspects of chirality and organocatalysis and an equally extensive experimental section that allow nonexperts to understand the discussion section and reproduce the experiments.

About the authors

Nicola Di Iorio was born in 1989. During his studies at the University of Bologna, Italy he spent a year abroad at UCLA (University of California, Los Angeles, USA) before graduating (cum laude) in Industrial Chemistry in October 2013. Immediately afterwards, he started his doctoral studies on asymmetric organocatalysis, focusing particularly on unconventional axial chirality. In February 2017 he received the “Spada Award” for Ph.D. students who have distinguished themselves in productivity, innovation and scientific independence. Two months later, he completed his Ph.D. and is currently working as a postdoc at the Department of Industrial Chemistry at the University of Bologna.

Table of contents (5 chapters)

  • Introduction

    Di Iorio, Nicola

    Pages 1-24

    Preview Buy Chapter 30,19 €
  • The Vinylogous Reactivity of Oxindoles Bearing Non-symmetric 3-Alkylidene Groups

    Di Iorio, Nicola

    Pages 25-60

    Preview Buy Chapter 30,19 €
  • Targeting the Remote Control of Axial Chirality in N-(2-tert-butylphenyl)Succinimides via a Desymmetrization Strategy

    Di Iorio, Nicola

    Pages 61-117

    Preview Buy Chapter 30,19 €
  • Direct Catalytic Synthesis of C(Sp2)–C(Sp3) Atropisomers with Simultaneous Control of Central and Axial Chirality

    Di Iorio, Nicola

    Pages 119-155

    Preview Buy Chapter 30,19 €
  • Conclusions and Future Outlooks

    Di Iorio, Nicola

    Pages 157-157

    Preview Buy Chapter 30,19 €

Buy this book

eBook 91,62 €
price for Spain (gross)
  • ISBN 978-3-319-74914-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 114,39 €
price for Spain (gross)
  • ISBN 978-3-319-74913-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules
Authors
Series Title
Springer Theses
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-74914-3
DOI
10.1007/978-3-319-74914-3
Hardcover ISBN
978-3-319-74913-6
Series ISSN
2190-5053
Edition Number
1
Number of Pages
XXI, 157
Number of Illustrations and Tables
5 b/w illustrations, 28 illustrations in colour
Topics