The Bethesda System for Reporting Thyroid Cytopathology

1. Front Matter

   Pages i-xv

   PDF

2. Overview of Diagnostic Terminology and Reporting

   • Zubair W. Baloch, David S. Cooper, Hossein Gharib, Erik K. Alexander

   Pages 1-6

3. Nondiagnostic/Unsatisfactory

   • Barbara A. Crothers, Michael R. Henry, Pinar Firat, Mary C. Frates, Esther Diana Rossi

   Pages 7-18

4. Benign

   • Tarik M. Elsheikh, Béatrix Cochand-Priollet, Soon Won Hong, Mary K. Sidawy

   Pages 19-48

5. Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance

   • Jeffrey F. Krane, Ritu Nayar, Andrew A. Renshaw

   Pages 49-70

6. Follicular Neoplasm/Suspicious for a Follicular Neoplasm

   • Michael R. Henry, William H. Westra, Jeffrey F. Krane, Fernando Schmitt

   Pages 71-80

7. Follicular Neoplasm, Hürthle Cell (Oncocytic) Type/Suspicious for a Follicular Neoplasm, Hürthle Cell (Oncocytic) Type

   • William C. Faquin, Claire W. Michael, Andrew A. Renshaw, Philippe Vielh

   Pages 81-100

8. Suspicious for Malignancy

   • Paul A. VanderLaan, Ashish Chandra, Armando C. Filie, Gregory W. Randolph, Celeste N. Powers

   Pages 101-118

9. Papillary Thyroid Carcinoma, Variants, and Related Tumors

   • Marc P. Pusztaszeri, Manon Auger, Edward B. Stelow, Grace C. H. Yang, Miguel A. Sanchez, Virginia A. LiVolsi

   Pages 119-156

10. Medullary Thyroid Carcinoma

    • Michiya Nishino, Marc P. Pusztaszeri, Martha B. Pitman

    Pages 157-175

11. Poorly Differentiated Thyroid Carcinoma

    • Massimo Bongiovanni, Guido Fadda, William C. Faquin

    Pages 177-188

12. Undifferentiated (Anaplastic) Carcinoma and Squamous Cell Carcinoma of the Thyroid

    • Gregg A. Staerkel, Justin A. Bishop, Vinod B. Shidham, Matthew A. Zarka

    Pages 189-204

13. Metastatic Tumors, Lymphomas, and Rare Tumors of the Thyroid

    • Lester J. Layfield, Kennichi Kakudo

    Pages 205-230

14. Back Matter

    Pages 231-236

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  The first edition of The Bethesda System for Reporting Thyroid Cytopathology was published in 2010 and has greatly influenced the practice of thyroid cytopathology. The terminology proposed and illustrated in this text has been widely adopted not only in the U.S. but also abroad. It has become an essential text for pathology trainees and practicing pathologists examining thyroid fine needle aspiration (FNA) specimens.


  Since 2010, there have been a number of important advances in the management of patients with nodular thyroid disease and in the understanding of the biology of thyroid cancer. This new edition includes these advances that impact terminology for reporting thyroid cytopathology. In particular, it incorporates a discussion of the recently implemented and now widespread use of molecular testing of thyroid FNA samples, which has transformed the management of patients with nodular thyroid disease in the U.S.. In addition, this edition accommodates the recent changes to the classification of thyroid cancer, most notably the introduction of a new thyroid diagnosis, that of "non-invasive follicular tumor with papillary-like nuclear features (NIFTP)".


  Thoroughly revised and updated, The Bethesda System for Reporting Thyroid Cytopathology, Second Edition will provide the reader with a unified approach to diagnosing and reporting thyroid FNA interpretations. It serves as a reference guide not just for pathologists, but also endocrinologists, surgeons, and radiologists.

• cancer
• cell
• cytology
• cytopathology
• lymphoma
• Follicular Neoplasm
• Medullary Thyroid Carcinoma
• Metastatic Tumors
• surgical oncology

“This is the second edition of the most widely accepted standard for reporting thyroid cytopathology. … This book is aimed at pathologists, pathology trainees, and cytopathology technologists. The book also provides useful information for endocrinologists, surgeons, and radiologists. … This is a valuable resource for pathologists and provides important updates to the original edition. It maintains and updates the original classification scheme while also providing an excellent atlas, explanatory notes, and clinical utility.” (Brian S. Soles, Doody's Book Reviews, February, 2018)

• Department of Pathology, The Johns Hopkins Hospital/The Johns Hopkins University School of Medicine, Baltimore, USA

  Syed Z. Ali

• Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, USA

  Edmund S. Cibas

Syed Z. Ali, MD


Professor of Pathology


The Johns Hopkins Hospital


Baltimore, MD


USA





Edmund S. Cibas, MD


Professor of Pathology


Harvard Medical School


Brigham and Women's Hospital


Boston, MA


USA

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