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Vasoplegic Endothelial Dysfunction

Circulatory Shock and Methylene Blue

Authors: Barbosa Evora, P.R., Celotto, A.C., Afrodite Sumarelli Albuquerque, A., Martinez Évora, P.

  • Covers cardiocirculatory shock in a comprehensive yet easy-to-read format
  • Broadens understanding of Methylene Blue
  • Shares the knowledge of a highly experienced authority in the field of Cardiovascular Surgery
  • Collates worldwide experimental and clinical cases
  • Appeals to a wide range of health professionals
  • Sets the direction for future research
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書籍の購入

イーブック ¥14,871
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • イーブック版は、まもなく発売予定です。
  • 予定日: June 30, 2021
  • ISBN 978-3-030-74096-2
  • ウォーターマーク付、 DRMフリー
  • ファイル形式:
  • ebooks can be used on all reading devices
ハードカバー ¥18,589
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • 予定日: June 30, 2021
  • ISBN 978-3-030-74095-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
この書籍について

This unique work presents one of the most significant organ failure condition – cardiocirculatory shock – and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors’ consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients.

In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned.

Finally, looking for therapeutic alternatives for what we classify as "vasoplegic endothelial dysfunction", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are "wide-spectrum vasopressors", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines.

This book´s translational approach will appeal to a variety of readers within the health specialties of medicine, biomedicine, physiotherapy, nursing, odontology, and basic science.

著者について

Paulo Roberto Barbosa Evora

Graduated in Medicine from the Ribeirão Preto School of Medicine, University of São Paulo – USP (1972). At the same institution, he completed residencies in General Surgery (1973) and Thoracic and Cardiovascular Surgery (1974), and a PhD also in General Surgery (1980). Dr. Evora was Coordinator of the Endothelial Function Laboratory of the Experimental Surgery Division and Collaborating Researcher in Cardiovascular Surgical Research at the Mayo Clinic, Rochester, MN, USA. Associate Professor (1994) and Full Professor (2004) of the Department of Surgery, Orthopedics and Traumatology at the Ribeirão Preto School of Medicine, USP (1993), clinical director of the Intensive Care Center at the Hospital das Clínicas of the Ribeirão Preto School of Medicine - USP, Coordinator of the postgraduate program (2004-2006), Vice-Head of the Department (2004-2006), Head of the Department (2007-2008), member of the Research Committee of the Ribeirão Preto School of Medicine, and member of the Bioterio Central Commission of the USP Ribeirão Preto Campus, and Editor-in-chief of the Brazilian Journal of Cardiovascular Surgery.

 

Andrea Carla Celotto

Graduated in Biomedicine from the University of Franca (2002), obtained a Master’s degree in Pharmaceutical Sciences from the Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo - USP (2005), and completed a PhD in Sciences at the Ribeirão Preto School of Medicine - USP (2009). She also completed a PhD internship at the Vascular Biology Laboratory at Mayo Clinic, Rochester, MN, USA and a post-doctorate at the Endothelial Function Laboratory of the Department of Surgery and Anatomy at Ribeirão Preto School of Medicine - USP (2013). Former professor at the University of Franca, Dr. Celotto is currently a professor of the Faculty of Health Sciences of Barretos Dr. Paulo Prata and an Associate Researcher of the Department of Surgery and Anatomy, Ribeirão Preto School of Medicine – USP. She has extensive experience in Physiology, Pathophysiology and Pharmacology.

 

Agnes Afrodite Sumarelli Albuquerque

Bachelor’s degree in Biological Sciences from Universidade Estadual Paulista Júlio de Mesquita Filho, Jaboticabal campus (2005) and specialization in Genetic Engineering and Molecular Biology (2009). She obtained a Master’s degree (2012) and completed a PhD (2018) in Morphology and Experimental Medicine Surgical Clinic. Laboratory Technician at the Department of Surgery and Anatomy of the Ribeirão Preto Medical School of the University of São Paulo.

 

Patricia Martinez Évora

Graduated in Veterinary Medicine from the Universidade Estadual Paulista Júlio de Mesquita Filho, Jaboticabal campus (2008). Completed internships at Ohio State University, Columbus, OH, USA, in the fields of equine medical clinic and Molecular Biology (2008). She obtained a Master's degree in Veterinary Medicine (2012) and completed a PhD in Animal Pathology from the Universidade Estadual Paulista Júlio de Mesquita Filho, Jaboticabal campus (2017). Dr. Évora is currently a postdoctoral fellow in Immunoparasitology at the Ribeirão Preto School of Medicine - USP.

書籍の購入

イーブック ¥14,871
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • イーブック版は、まもなく発売予定です。
  • 予定日: June 30, 2021
  • ISBN 978-3-030-74096-2
  • ウォーターマーク付、 DRMフリー
  • ファイル形式:
  • ebooks can be used on all reading devices
ハードカバー ¥18,589
価格の適用国: Japan (日本円価格は個人のお客様のみ有効) (小計)
  • 予定日: June 30, 2021
  • ISBN 978-3-030-74095-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
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書誌情報

Bibliographic Information
Book Title
Vasoplegic Endothelial Dysfunction
Book Subtitle
Circulatory Shock and Methylene Blue
Authors
Copyright
2021
Publisher
Springer International Publishing
Copyright Holder
The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG
イーブック ISBN
978-3-030-74096-2
DOI
10.1007/978-3-030-74096-2
ハードカバー ISBN
978-3-030-74095-5
Edition Number
1
Number of Pages
XXI, 144
Number of Illustrations
11 b/w illustrations, 3 illustrations in colour
Additional Information
Original Portuguese edition published by Editora Atheneu Ltda., São Paulo, Brazil, 2011
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