Editors:
- Presents fundamental physics and engineering concepts of dynamic hyperpolarized NMR and illustrates the current biomedical applications
- Defines characteristic properties of hyperpolarizable molecules
- Shows current biomedical applications to gather insights into in vivo metabolic regulation and control
Part of the book series: Handbook of Modern Biophysics (HBBT)
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Table of contents (10 chapters)
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Front Matter
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Back Matter
About this book
This is the first book in the series to focus on dynamic hyperpolarized nuclear magnetic resonance, a burgeoning topic in biophysics. The volume follows the format and style of the Handbook of Modern Biophysics series and expands on topics already discussed in previous volumes. It builds a theoretical and experimental framework for students and researchers who wish to investigate the biophysics and biomedical application of dynamic hyperpolarized NMR. All contributors are internationally recognized experts, lead the dynamic hyperpolarized NMR field, and have first-hand knowledge ofthe chapter material.
The book covers the following topics:
- Hyperpolarization by dissolution Dynamic Nuclear Polarization
- Design considerations for implementing a hyperpolarizer Chemical Shift Imaging with Dynamic Hyperpolarized NMR
- Signal Sampling Strategies in Dynamic Hyperpolarized NMR Kinetic Modeling of Enzymatic Reactions in Analyzing Hyperpolarized NMR Data
- Using Hyperpolarized NMR to Understand Biochemistry from Cells to Humans Innovating Metabolic Biomarkers for Hyperpolarized NMR
- New Insights into Metabolic Regulation from Hyperpolarized 13C MRS/MRI Studies Novel Views on Heart Function from Dynamic Hyperpolarized NMR
- Insights on Lactate Metabolism in Skeletal Muscle based on 13C Dynamic Nuclear Polarization Studies
About the Editors
Dirk Mayer is Professor of Diagnostic Radiology and Nuclear Medicine at the University of Maryland and is the Director of Metabolic Imaging. He is a recognized expert on dynamic nuclear polarization (DNP) MRI-based imaging techniques and has optimized acquisition and reconstruction techniques, has constructed kinetic modeling for quantitative analysis, and has developing new probes.
Thomas Jue is Professor of Biochemistry and Molecular Medicine at the University of California Davis. He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo. He served as a Chair of the Biophysics Graduate Group Program at UC Davis, where he started to redesign a graduate curriculum that balances physical science/mathematics formalism and biomedical perspective in order to promote interest at the interface of physical science, engineering, mathematics, biology, and medicine. The Handbook of Modern Biophysics represents an aspect of that effort.
Editors and Affiliations
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Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, USA
Thomas Jue
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Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, Baltimore, USA
Dirk Mayer
About the editors
Thomas Jue, Ph.D. Professor Department of Biochemistry and Molecular Medicine, University of California Davis He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo and has published extensively in the field of magnetic resonance spectroscopy and imaging, near-infrared spectroscopy, bioenergetics, cardiovascular regulation, exercise, and marine biology. He served as a Chair of the Biophysics Graduate Group Program at UC Davis, where he started to redesign a graduate curriculum that balances physical science/mathematics formalism and biomedical perspective in order to promote interest at the interface of physical science, engineering, mathematics, biology, and medicine.The Handbook of Modern Biophysics represents an aspect of that effort.
Dirk Mayer
Dirk Mayer Associate Professor of Diagnostic Radiology and Nuclear Medicine at theUniversity of Maryland and Director of Metabolic Imaging. He is a recognized expert on dynamic nuclear polarization (DNP) and MRI-based imaging techniques.He has optimized acquisition and reconstruction techniques, has constructed kinetic models for quantitative analysis, and has developed new biomolecular probes. His research focuses on using DNP to discover new approaches in tumor diagnosis and inmonitoring and assessing cardiovascular and liver pathologies, inflammatory diseases, and brain metabolism.
Bibliographic Information
Book Title: Dynamic Hyperpolarized Nuclear Magnetic Resonance
Editors: Thomas Jue, Dirk Mayer
Series Title: Handbook of Modern Biophysics
DOI: https://doi.org/10.1007/978-3-030-55043-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2021
Hardcover ISBN: 978-3-030-55041-7Published: 22 May 2021
eBook ISBN: 978-3-030-55043-1Published: 21 May 2021
Series ISSN: 2698-380X
Series E-ISSN: 2698-3818
Edition Number: 1
Number of Pages: XIII, 279
Number of Illustrations: 14 b/w illustrations, 59 illustrations in colour
Topics: Biomedical Engineering and Bioengineering, Biological and Medical Physics, Biophysics