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Fluorescent Imaging in Medicinal Chemistry

  • Book
  • © 2020

Overview

Editors:
  1. Zhen Cheng

    1. Stanford University, Stanford, USA

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  • Outlines the cutting-edge developments in fluorescent imaging techniques for medicinal chemistry research
  • Reviews the biomedical applications of fluorescent imaging techniques, ranging from in vitro assay, in vivo imaging, to clinical applications
  • Presents an authoritative work across chemistry, materials, biology, and medicine

Part of the book series: Topics in Medicinal Chemistry (TMC, volume 34)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-vii
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  2. Fluorescence Molecular Imaging of Medicinal Chemistry in Cancer

    • Jie Tian, Yang Du, Chu Tang, Yu An
    Pages 1-31

  3. Organic Fluorescent Probes for Diagnostics and Bio-Imaging

    • Xingyue Yang, Jonathan F. Lovell, Niren Murthy, Yumiao Zhang
    Pages 33-53

  4. Inorganic Fluorescent Nanomaterials

    • Taeho Kim, Jesse V. Jokerst
    Pages 55-80

  5. Advancements of Second Near-Infrared Biological Window Fluorophores: Mechanism, Synthesis, and Application In Vivo

    • Shuqing He, Zhen Cheng
    Pages 81-123

  6. X-Ray Excited Fluorescent Materials for Medical Application

    • Don Vernekohl, Lei Xing
    Pages 125-148

  7. Applications of Fluorescent Protein-Based Sensors in Bioimaging

    • Uday Kumar Sukumar, Arutselvan Natarajan, Tarik F. Massoud, Ramasamy Paulmurugan
    Pages 149-183

  8. Fluorescent Probes for Diagnostics of β-Galactosidase: From Micro to Macro

    • Anyao Bi, Xinchen Jiang, Tang Gao, Shuqi Yang, Yi Liu, Xiaohui Liu et al.
    Pages 185-201

  9. The Present and Future of Optical Imaging Technologies in the Clinic: Diagnosis and Therapy

    • Evan P. Stater, Magdalena Skubal, Ryo Tamura, Jan Grimm
    Pages 203-223

  10. Back Matter

    Pages 225-228
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Keywords

About this book

This book reviews the most recent developments of fluorescent imaging techniques for medicinal chemistry research and biomedical applications, including cell imaging, in vitro diagnosis and in vivo imaging.

Fluorescent imaging techniques play an important role in basic research, drug discovery and clinical translation. They have great impact to many fields including chemical biology, cell biology, medical imaging, cancer diagnosis and treatment, pharmaceutical science, among others, and they have facilitated our understanding of diseases and helped to develop many novel powerful tools for imaging and treatment of diseases.

This book will appeal to scientists from numerous fields such as chemistry, pharmaceutical science, biology, materials science, and medicine, and it will serve as a very useful and handy resource for readers with different levels of scientific knowledge, ranging from entry level to professional level.

Editors and Affiliations

  • Stanford University, Stanford, USA

    Zhen Cheng

About the editor

Dr. Zhen Cheng is Associate Professor of Radiology and a member of the Molecular Imaging Program at Stanford (MIPS), BioX program, Canary Center at Stanford for Cancer Early Detection, and Stanford Cancer Center. He currently leads the Cancer Molecular Imaging Chemistry Laboratory (CMICL) of the MIPS, where he is developing novel molecular probes, non-invasive imaging techniques and bionanotechnology for the early detection and treatment of cancer. Dr. Cheng earned his PhD in Chemistry from University of Missouri-Columbia in 2001 and completed his post-doc training at Harvard Medical School in 2003. Dr. Cheng has published over 200 peer-reviewed articles. He has served as a reviewer for several funding agencies including NIH, DOD, DOE, etc. and also as an active reviewer for over 100 research journals. 

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