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  • © 2019

Landmark Trials in Oncology

Authors:

  • Details how cancer is treated through the lens of approximately 250 clinical trials
  • Relevant and informative across the disciplines of surgery, medical oncology, and radiation oncology
  • Concise and focused on the great clinical trials and how they have shaped current cancer treatment
  • 9988 Accesses

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-ix
  2. Landmark Trials in Breast Cancer

    • Santosh Yajnik
    Pages 7-40
  3. Landmark Trials in Lung Cancer

    • Santosh Yajnik
    Pages 41-74
  4. Landmark Trials in Selected Lymphomas

    • Santosh Yajnik
    Pages 241-272
  5. Back Matter

    Pages 319-325

About this book

This book describes the evolution of treatment in oncology through the lens of approximately 250 landmark clinical trials. The well-designed clinical trial is essential to the practice of medicine. There is no field that has embraced or been transformed more by the clinical trial than oncology. 

Each primary cancer site has a remarkable story that can be told through clinical trials.  For example, patients who presented decades ago with soft tissue sarcoma of the extremities would invariably undergo limb amputation.  The landmark National Cancer Institute study by Rosenberg et al. randomized patients to limb sparing surgery followed by adjuvant radiation therapy compared with limb amputation.  This study helped change the standard of care by allowing most patients to retain their functioning limbs with an improvement in quality of life and no compromise in overall survival.  Such major clinical trials for common malignancies including breast, prostate, lung, gastrointestinal, genitourinary, and gynecologic cancers are discussed. 

Because oncology is multidisciplinary, this book should be of interest for radiation oncologists, surgeons, medical oncologists, and other physicians interested in learning more about the landmark trials that have shaped oncology.

Reviews

“The book likely will be of greatest interest to resident radiation oncology and surgery physicians preparing for oral boards, as well as medical oncology fellows. … This is an admirable addition to the oncology literature. … This book speaks to the value of recognizing and understanding clinical trials and provides an alternative approach to achieving this worthy end. It also provides a refreshing approach for trainees seeking mastery of the oncology literature.” (Mark D. Hurwitz, Doody's Book Reviews, 27 September, 2019)

Authors and Affiliations

  • Radiation Oncology Consultants (ROC), Chicago, USA

    Santosh Yajnik

About the author

Santosh V. Yajnik, M.D. is a radiation oncologist with Radiation Oncology Consultants.  He is Medical Director of Radiation Oncology and Chair of the Cancer Committee at Advocate Illinois Masonic Medical Center.  He has published widely in radiation oncology and is author of Proton Beam Therapy (Springer, 2013).

Bibliographic Information

  • Book Title: Landmark Trials in Oncology

  • Authors: Santosh Yajnik

  • DOI: https://doi.org/10.1007/978-3-030-14405-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-14404-3Published: 22 May 2019

  • Softcover ISBN: 978-3-030-14407-4Published: 15 August 2020

  • eBook ISBN: 978-3-030-14405-0Published: 17 May 2019

  • Edition Number: 1

  • Number of Pages: IX, 325

  • Number of Illustrations: 50 b/w illustrations, 70 illustrations in colour

  • Topics: Radiotherapy, Oncology, Surgical Oncology

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access