Atlas of Bone Marrow Pathology

1. Front Matter

   Pages i-xiv

   PDF

2. Normal Bone Marrow

   • Heesun J. Rogers

   Pages 1-12

3. Reactive Changes

   • Rebecca L. King, Matthew T. Howard

   Pages 13-26

4. Post-therapy Marrow Changes

   • Jason H. Kurzer, Olga K. Weinberg

   Pages 27-32

5. Constitutional, Metabolic, and Related Disorders

   • Kristian T. Schafernak, Katherine R. Calvo

   Pages 33-66

6. Bone Marrow Infections

   • Ahmad Monabati, Girish Venkataraman, Perikala Vijayananda Kumar

   Pages 67-76

7. Bone Marrow Lymphoma

   • Megan Parilla, Girish Venkataraman

   Pages 77-102

8. Plasma Cell Neoplasms

   • Carla S. Wilson

   Pages 103-116

9. Immunodeficiency-Associated Lymphoproliferative Disorder

   • Juehua Gao, Yi-Hua Chen

   Pages 117-127

10. Lymphoblastic Leukemia/Lymphoma

    • Qian-Yun Zhang

    Pages 129-157

11. Myelodysplastic Syndrome

    • Sandeep Gurbuxani

    Pages 159-171

12. Acute Myeloid Leukemia

    • Daniel A. Arber

    Pages 173-191

13. Myeloid Proliferations of Down Syndrome

    • Lee J. McGhan, Maria A. Proytcheva

    Pages 193-198

14. Acute Leukemias of Ambiguous Lineage

    • Min Shi, Kaaren K. Reichard

    Pages 199-209

15. Histiocytic Disorders

    • Payal Sojitra, Tracy I. George

    Pages 211-222

16. Myeloproliferative Neoplasms and Mastocytosis

    • Luke R. Shier, Tracy I. George

    Pages 223-255

17. Myeloid and Lymphoid Neoplasms with Eosinophilia

    • Joanna M. Chaffin, Natasha Marie Savage

    Pages 257-265

18. Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)

    • Aaron Paul Rupp, Devon Chabot-Richards

    Pages 267-276

19. Metastatic Tumors in the Bone Marrow

    • Mohammad Vasef

    Pages 277-287

20. Back Matter

    Pages 289-293

    PDF

This text illustrates bone marrow aspirate, imprint and biopsy specimens showing characteristic features of a wide variety of neoplastic and non-neoplastic conditions. While the focus is on Wright-stained smears and hematoxylin-eosin stained biopsies, other key histochemical and immunohistochemical stains are illustrated that are vital for proper diagnosis.  After a brief review of the normal bone marrow, reactive changes in the marrow are illustrated, including the bone marrow response in constitutional disorders and to metabolic changes throughout the body.  This is followed by specific infectious disorders in the marrow and other non-neoplastic disorders.  The remainder of the Atlas illustrates the various neoplasms that involve the bone marrow, including leukemias, lymphomas and non-hematopoietic neoplasms.  The hematologic neoplasms are classified using the 2016 World Health Organization (WHO) classification.  This overview of bone marrow disorders illustrates a wide variety of diseases that practicing pathologists and hematologists will encounter in their routine practice.​

• Cryptococcus
• Erythroid disorders
• Erythroid hyperplasia
• Fanconi anemia
• Follicular lymphoma
• Granulocyte disorders
• Hodgkin lymphoma
• Lymphoblastic Leukemias
• Megakaryocytes
• Mycobacteria
• Myelodysplastic Syndromes
• Plasma cell neoplasms
• myeloablative therapy

“This atlas is a welcome addition to the bone marrow pathology literature. It is an excellent quick reference for both common and rare bone marrow conditions. … This atlas will be a great quick reference for practicing pathologists, while residents and fellows can use it for board preparation. Furthermore, laboratory technologists also will find it useful for morphology review.” (Anamarija M. Perry, Doody's Book Reviews, May, 2018)

• Department of Pathology, University of New Mexico School of Medicine, Albuquerque, USA

  Tracy I. George

• Department of Pathology, The University of Chicago, Chicago, USA

  Daniel A. Arber

Tracey I. George, MD

Professor and Vice Chair of Clinical Affairs

Division Chief, Hematopathology

Department of Pathology

University of New Mexico Health Sciences Center

Albuquerque, NM, USA

Daniel A. Arber, MD

Professor and Chair

Department of Pathology

The University of Chicago

Chicago, IL ,USA

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