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Nanomedicines for Brain Drug Delivery

  • Book
  • © 2021

Overview

Editors:
  1. Javier O. Morales

    1. Department of Pharmaceutical Science and Technology, University of Chile, Santiago, Chile

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    You can also search for this editor in PubMed   Google Scholar

  2. Pieter J. Gaillard

    1. 2-BBB Medicines BV, Leiden, The Netherlands

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key note and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 157)

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Table of contents (10 protocols)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Biodegradable Polymeric Nanoparticles for Brain-Targeted Drug Delivery

    • Kristian Kempe, Joseph A. Nicolazzo
    Pages 1-27

  3. Liposomes as Brain Targeted Delivery Systems

    • Francesco Lai, Michele Schlich, Chiara Sinico, Anna Maria Fadda
    Pages 29-59

  4. Nanofibers and Nanostructured Scaffolds for Nervous System Lesions

    • Jose L. Gerardo Nava, Jonas C. Rose, Haktan Altinova, Paul D. Dalton, Laura De Laporte, Gary A. Brook
    Pages 61-101

  5. Self-Assembling Peptide Nanofibrous Scaffolds in Central Nervous System Lesions

    • Na Zhang, Liumin He, Wutian Wu
    Pages 103-117

  6. The Use of Peptide and Protein Vectors to Cross the Blood-Brain Barrier for the Delivery of Therapeutic Concentration of Biologics

    • Mei Mei Tian, Reinhard Gabathuler
    Pages 119-147

  7. Inorganic Nanoparticles and Their Strategies to Enhance Brain Drug Delivery

    • Eduardo Gallardo-Toledo, Carolina Velasco-Aguirre, Marcelo Javier Kogan
    Pages 149-172

  8. Magnetic Nanoparticles as Delivery Systems to Penetrate the Blood-Brain Barrier

    • Joan Estelrich, Maria Antònia Busquets
    Pages 173-208

  9. Nose-to-Brain Drug Delivery Enabled by Nanocarriers

    • Zachary Warnken, Yang Lu, Hugh D. C. Smyth, Robert O. Williams III
    Pages 209-233

  10. In Vitro Models of Central Nervous System Barriers for Blood-Brain Barrier Permeation Studies

    • Sounak Bagchi, Behnaz Lahooti, Tanya Chhibber, Sree-pooja Varahachalam, Rahul Mittal, Abhijeet Joshi et al.
    Pages 235-253

  11. Safety and Nanotoxicity Aspects of Nanomedicines for Brain-Targeted Drug Delivery

    • Johanna Catalan-Figueroa, Javier O. Morales
    Pages 255-277

  12. Back Matter

    Pages 279-280
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Keywords

About this book

This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process. Chapters in this book cover topics such as polymeric nanoparticles and liposomes; self-assembled peptide-based scaffolds for lesions of the nervous system; use of peptides as CNS drugs and as potential carriers to optimize brain-targeted delivery; ways to model and assess blood brain barrier absorption of drugs; and the role of neurodegeneration progress of nanomaterials and their potential toxicity concerns. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.


Thorough and cutting-edge, Nanomedicines for Brain Drug Delivery is a valuable resource that will help researchers guide and advance the field of nanomedicines for the brain and nervous system.

Editors and Affiliations

  • Department of Pharmaceutical Science and Technology, University of Chile, Santiago, Chile

    Javier O. Morales

  • 2-BBB Medicines BV, Leiden, The Netherlands

    Pieter J. Gaillard

Bibliographic Information

  • Book Title: Nanomedicines for Brain Drug Delivery

  • Editors: Javier O. Morales, Pieter J. Gaillard

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-0838-8

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2021

  • Hardcover ISBN: 978-1-0716-0837-1Published: 20 November 2020

  • Softcover ISBN: 978-1-0716-0840-1Published: 20 November 2021

  • eBook ISBN: 978-1-0716-0838-8Published: 19 November 2020

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XII, 280

  • Number of Illustrations: 6 b/w illustrations, 27 illustrations in colour

  • Topics: Neurosciences, Biomaterials, Biotechnology, Pharmacology/Toxicology

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