Read the latest JMR Editor’s Choice paper on biodegradable polyphosphazenes for regenerative engineering, freely accessible through April 2023!

At the invitation of the Editor-in-Chief, JMR has published “Biodegradable polyphosphazenes for regenerative engineering,” by Feiyang Chen, Oyindamola R. Teniola, and Cato T. Laurencin of UConn Health and the University of Connecticut.

Regenerative engineering is a field that seeks to reconstruct complex tissues and biological systems, rather than simply restore and repair individual tissues or organs. Since the first introduction of regenerative engineering in 2012, numerous research efforts have been devoted to the development of this field. Biodegradable polymers such as polyphosphazenes in particular have drawn significant interest as regenerative engineering materials for their synthetic flexibility in designing materials with a wide range of mechanical properties, degradation rates, and chemical functionality. These polyphosphazenes can go through complete hydrolytic degradation and provide harmless and pH-neutral buffering degradation products such as phosphates and ammonia, which is crucial for reducing inflammation in vivo.  

Written for a wider materials science readership, the authors discuss current accomplishments with polyphosphazenes, different methods for synthesizing them, and their applications in tissue regeneration such as bones, nerves and elastic tissues. 

JMR is pleased to publish this invited Editor’s Choice paper and offer it with free accessibility for a full year, through April 30, 2023.