Pharmacological Reports

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Volume 77, Issue 1

February 2025

20 articles in this issue

The future of metronomic chemotherapy: experimental and computational approaches of drug repurposing
Yousef A. Abdelrady
Hayam S. Thabet
Ahmed M. Sayed
Review 21 October 2024 Pages: 1 - 20
Long noncoding RNA MEG3: an active player in fibrosis
Xiaoying Jiang
Review 07 October 2024 Pages: 21 - 30
Acyclic sesquiterpenes nerolidol and farnesol: mechanistic insights into their neuroprotective potential
Anish Singh
Lovedeep Singh
Review 22 October 2024 Pages: 31 - 42
Impact of statin therapy on CD40:CD40L signaling: mechanistic insights and therapeutic opportunities
Fatemeh Askarizadeh
Sercan Karav
Amirhossein Sahebkar
Review 16 December 2024 Pages: 43 - 71
Ursolic acid in colorectal cancer: mechanisms, current status, challenges, and future research directions
Huici Zhang
Xiaoyu Zhang
Xuan Wang
Review 02 December 2024 Pages: 72 - 86
Anticancer potential of osthole: targeting gynecological tumors and breast cancer
Yingqi Han
Zhengao Sun
Review 02 December 2024 Pages: 87 - 102
A comprehensive update on the potential of curcumin to enhance chemosensitivity in colorectal cancer
Mahdi Shadnoush
Mehrnaz Momenan
Makan Cheraghpour
Review 20 September 2024 Pages: 103 - 123
Progress in the study of anti-tumor effects and mechanisms of vitexin
Qiming Yang
Rui Huan
Lei Xia
Review 31 October 2024 Pages: 124 - 134
Assessing the effects of 5-HT_2A and 5-HT_5A receptor antagonists on DOI-induced head-twitch response in male rats using marker-less deep learning algorithms
Ewelina Cyrano
Piotr Popik
Research Open access 27 November 2024 Pages: 135 - 144
Proteomics analysis in rats reveals convergent mechanisms between major depressive disorder and dietary zinc deficiency
Łukasz Gąsior
Bartłomiej Pochwat
Bernadeta Szewczyk
Research Open access 03 December 2024 Pages: 145 - 157
Advanced pharmacological and pharmacokinetic evaluation of 1,3 dimethylpurine-2,6-dione derivative (GR-14) with prominent mood-modulating activity in rats
Agnieszka Cios
Grażyna Chłoń-Rzepa
Anna Wesołowska
Research 16 December 2024 Pages: 158 - 171
Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A_2a receptors
Caleb A. Seekins
Alyssa M. Welborn
John M. Streicher
Research 12 December 2024 Pages: 172 - 181
c-Myc inhibition and p21 modulation contribute to unsymmetrical bisacridines-induced apoptosis and senescence in pancreatic cancer cells
Agnieszka Kurdyn
Monika Pawłowska
Ewa Augustin
Research Open access 03 October 2024 Pages: 182 - 209
Inhibition of CHI3L1 decreases N-cadherin and VCAM-1 levels in glioblastoma
Agnieszka Rusak
Marlena Gąsior-Głogowska
Piotr Dzięgiel
Research Open access 14 November 2024 Pages: 210 - 228
ONC206, an imipridone derivative, demonstrates anti-colorectal cancer activity against stem/progenitor cells in 3D cell cultures and in patient-derived organoids
Alissar Monzer
Fatima Ghamlouche
Wassim Abou-Kheir
Research 18 November 2024 Pages: 229 - 246
Effects of puerarin on gait disturbance in a 6-hydroxydopamine mouse model of Parkinson’s disease
Na-Hyun Kim
Yukiori Goto
Young-A Lee
Research 28 October 2024 Pages: 247 - 259
JG26 attenuates ADAM17 metalloproteinase-mediated ACE2 receptor processing and SARS-CoV-2 infection in vitro
Valentina Gentili
Silvia Beltrami
Elisa Nuti
Research Open access 18 September 2024 Pages: 260 - 273
Safety of dapagliflozin and empagliflozin in cases with diabetes mellitus or/and heart failure: a retrospective pharmacovigilance study conducted on the eudravigilance database
Annamaria Mascolo
Alessia Zinzi
Annalisa Capuano
Research 23 October 2024 Pages: 274 - 286
A hydrogen sulphide-releasing non-steroidal anti-inflammatory, ATB-346, significantly attenuates human myometrial contractions
Ana Mijušković
Susan Wray
Sarah Arrowsmith
Short Communication Open access 04 September 2024 Pages: 287 - 294
Novel fluorinated cannabinoid analogs modulate cytokine expression in human C20 microglial cells
Randall L. Davis
Sascha Grotjahn
Jimmie D. Weaver III
Brief Communication 29 November 2024 Pages: 295 - 301

Volume 77, Issue 1

The future of metronomic chemotherapy: experimental and computational approaches of drug repurposing

Long noncoding RNA MEG3: an active player in fibrosis

Acyclic sesquiterpenes nerolidol and farnesol: mechanistic insights into their neuroprotective potential

Impact of statin therapy on CD40:CD40L signaling: mechanistic insights and therapeutic opportunities

Ursolic acid in colorectal cancer: mechanisms, current status, challenges, and future research directions

Anticancer potential of osthole: targeting gynecological tumors and breast cancer

A comprehensive update on the potential of curcumin to enhance chemosensitivity in colorectal cancer

Progress in the study of anti-tumor effects and mechanisms of vitexin

Assessing the effects of 5-HT_2A and 5-HT_5A receptor antagonists on DOI-induced head-twitch response in male rats using marker-less deep learning algorithms

Proteomics analysis in rats reveals convergent mechanisms between major depressive disorder and dietary zinc deficiency

Advanced pharmacological and pharmacokinetic evaluation of 1,3 dimethylpurine-2,6-dione derivative (GR-14) with prominent mood-modulating activity in rats

Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A_2a receptors

c-Myc inhibition and p21 modulation contribute to unsymmetrical bisacridines-induced apoptosis and senescence in pancreatic cancer cells

Inhibition of CHI3L1 decreases N-cadherin and VCAM-1 levels in glioblastoma

ONC206, an imipridone derivative, demonstrates anti-colorectal cancer activity against stem/progenitor cells in 3D cell cultures and in patient-derived organoids

Effects of puerarin on gait disturbance in a 6-hydroxydopamine mouse model of Parkinson’s disease

JG26 attenuates ADAM17 metalloproteinase-mediated ACE2 receptor processing and SARS-CoV-2 infection in vitro

Safety of dapagliflozin and empagliflozin in cases with diabetes mellitus or/and heart failure: a retrospective pharmacovigilance study conducted on the eudravigilance database

A hydrogen sulphide-releasing non-steroidal anti-inflammatory, ATB-346, significantly attenuates human myometrial contractions

Novel fluorinated cannabinoid analogs modulate cytokine expression in human C20 microglial cells

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