Special Issue on Sporotrichosis: challenges to deal with the new emerging pathogenic species
Sporotrichosis is a subcutaneous mycosis caused by Sporothrix schenckii, Sporothrix brasiliensis and Sporothrix globosa. This mycosis has gained importance in Latin America and Asia in the last decade due to the emergence of S. brasiliensis and S. globosa, two new pathogenic species, which are linked to zoonosis and sapronosis, respectively. In addition, S. brasiliensis infection has changed the old paradigm of sporotrichosis caused by Sporothrix schenckii sensu stricto. This highly virulent species can infect humans and animals, causing atypical and severe clinical manifestations in humans and domestic cats. In view of the emerging importance of S. brasiliensis and S. globosa, this special issue will focus on topics related to sporotrichosis caused by these new emerging species.
Deadline for submissions: December 1st 2019
AIM AND SCOPE
For more than a century, sporotrichosis was attributed to a single etiological agent: S. schenckii. Moreover, the disease caused by this fungus was considered a benign subcutaneous mycosis acquired by traumatic implantation in the skin of plant debris, thorns and other contaminated materials. The disease paradigm changed in 2007 following the description of new cryptic pathogenic species, S. brasiliensis and S. globosa. During the last decade, these two new species, recently included in the Pathogenic Clade of the Sporothrix genus, have gained clinical and epidemiological importance.
Sporothrix brasiliensis can infect humans and animals, be directly transmitted from animals to humans mainly by domestic cats (Felis catus), and is being linked to the major zoonotic outbreak of sporotrichosis described in the international literature. Today in Brazil, thousands of humans and domestic cats are infected by this highly virulent new species. At the same time, hundreds of cases of sporotrichosis caused by S. globosa have already been reported in China.
As such, there is a pressing need for further information in order to improve the epidemiological and clinical management of sporotrichosis related to these new emerging species. In addition, a better understanding of the host-fungus interplay, as well as the virulence factors, immunological response and other relevant biological aspects of Sporothrix spp is required. This volume aims to gather and present the findings of scientific studies carried out by experts on a diverse range of subjects mainly related to S. brasiliensis and S. globosa infection. We expect these findings to promote interest and actions on sporotrichosis management among the wider public and political institutions.
GUEST EDITOR TEAM
Dr. Leila M Lopes Bezerra, Universidade de São Paulo. Brazil
Dr. Sandro R. Almeida, Universidade de São Paulo, Brazil
Manuscripts should be formatted according to the journal’s submission guidelines and submitted via the online submission system.
IMPORTANT: You will be inquired, during the submission process, if your manuscript is part of a special issue. Please respond “yes” and select the option “Sporotrichosis”.