Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

Skip to main content

Welcome

Journal of CheminformaticsJournal of Cheminformatics is an open-access journal publishing original peer-reviewed research in all aspects of cheminformatics and molecular modelling.

Collection open to submissions

Evaluating AI and machine learning models in cheminformatics: benchmarking techniques and case studies

This collection aims to advance the field by presenting benchmarking methodologies and case studies that highlight the use of AI and machine learning models in cheminformatics. We seek contributions that provide detailed evaluations of computational tools, innovative benchmarking frameworks, and comprehensive case studies demonstrating the effectiveness of these models in predicting chemical properties.

Featured article

Chemical space as a unifying theme for chemistry

Chemistry has diversified from a basic understanding of the elements to studying millions of highly diverse molecules and materials, which together are conceptualized as the chemical space. A map of this chemical space where distances represent similarities between compounds can represent the mutual relationships between different subfields of chemistry and help the discipline to be viewed and understood globally.

Featured collections

A picture of a circuit board © Michael Schwarzenberger from Pixabay (CC0)Milestones in Cheminformatics

This special collection of commentaries is introduced for celebrating the 15th anniversary of the Journal of Cheminformatics. Pioneers and experts presents the greatest of all concepts, methodologies, and developments that have pushed the boundaries of cheminformatics to its current form, as well as forthcoming challenges and opportunities.

New Content Item © Pietro Jeng on UnsplashAI in Drug Discovery

The dramatic increase in the use of Artificial Intelligence (AI) and traditional machine learning methods in different scientific fields has become an essential asset in the future development of the chemical industry, including the pharmaceutical, agro biotech, and other chemical sectors. This collection discusses about the cutting-edge contributions in the rapidly evolving field of AI-driven drug discovery. 

Articles

2025

Evaluating AI and machine learning models in cheminformatics: benchmarking techniques and case studies
Open for submission

Research from the 13th International Conference on Chemical Structures
Open for submission

2024

Milestones in Cheminformatics
Closed. This collection is no longer accepting submissions.

AI in Drug Discovery
Closed. This collection is no longer accepting submissions.

2023

Research from the Ninth Joint Sheffield Conference on Chemoinformatics
Started publishing: 21 December 2023

Improving Reproducibility and Reusability in the Journal of Cheminformatics
Started publishing: 30 June 2023

2022

Research from 12th International Conference on Chemical Structures
Started publishing: 3 October 2022

Diversifying cheminformatics
Started publishing: 2 August 2022

2021

Biomedical Data Analyses Facilitated by Open Cheminformatics Workflows
Edited by Eva Nittinger, Alex Clark, Anna Gaulton, Barbara Zdrazil
Started publishing: 2 July 2021

2020

In Silico Structure Generation: Recent Developments, Applications, and Challenges
Edited by José L. Medina-Franco, Emma Schymanski, Christoph Steinbeck
Started publishing: 27 October 2020

Citation Typing Ontology (CiTO) Pilot
Edited by Egon Willighagen
Started publishing: 28 July 2020

2019

Big Data in Chemistry
Edited by Igor V. Tetko
Started publishing: 8 August 2019

Proceedings of the 11th International Conference on Chemical Structures
Edited by Gerard van Westen and Markus Wagener
Started publishing: 14 February 2019

Programming Languages for Chemical Information
Edited by Rajarshi Guha
Started publishing: 5 February 2019

2018

BioCreative V.5
Edited by Martin Krallinger, Obdulia Rabal, Anália Lourenço, Alfonso Valencia
Started publishing: 14 December 2018

Novel applications of machine learning in cheminformatics
Edited by Ola Spjuth
Started publishing: 21 February 2018

2015

Cross journal collection
Jean-Claude Bradley Memorial Series
Edited by Andrew SID Lang, Antony Williams
Started publishing: 22 March 2015

2013

6th Joint Sheffield Conference on Chemoinformatics
Started publishing: 29 July 2013

2012

The IUPAC International Chemical Identifier (InChI) and its influence on the domain of chemical information
Edited by Antony Williams
Started publishing: 13 December 2012

Semantic physical science
Edited by Henry Rzepa, Peter Murray-Rust
Started publishing: 3 August 2012

2011

Visions of a semantic molecular future
Started publishing: 14 October 2011

RDF technologies in chemistry
Edited by Egon Willighagen, Martin Paul Braendle
Started publishing: 13 May 2011

PubChem3D
Started publishing: 27 January 2011

2023

Improving reproducibility and reusability in the Journal of Cheminformatics
Charles Tapley Hoyt, Barbara Zdrazil, Rajarshi Guha, Nina Jeliazkova, Karina Martinez-Mayorga & Eva Nittinger 
30 June 2023

Are new ideas harder to find? A note on incremental research and Journal of Cheminformatics’ Scientific Contribution Statement
Barbara Zdrazil, Rajarshi Guha, Karina Martinez-Mayorga & Nina Jeliazkova 
15 January 2024

Biomedical data analyses facilitated by open cheminformatics workflows
Eva Nittinger, Alex Clark, Anna Gaulton & Barbara Zdrazil
17 April 2023 

A look back at a pilot of the citation typing ontology
Rajarshi Guha, Barbara Zdrazil, Nina Jeliazkova & Karina Martinez-Mayorga
3 February 2023 

2022

Diversifying cheminformatics
Barbara Zdrazil and Rajarshi Guha
25 April 2022

2021

What is the role of cheminformatics in a pandemic?
Rajarshi Guha, Egon Willighagen, Barbara Zdrazil & Nina Jeliazkova 
2 March 2021

2020

From Big Data to Artificial Intelligence: chemoinformatics meets new challenges
Igor V. Tetko & Ola Engkvist 
18 December 2020

Adoption of the Citation Typing Ontology by the Journal of Cheminformatics
Egon Willighagen
28 July 2020

Learning cheminformatics
Rajarshi Guha & Egon Willighagen
20 January 2020

2019

Journal of Cheminformatics, ORCID, and GitHub
Egon Willighagen, Nina Jeliazkova & Rajarshi Guha
8 July 2019

Implementing cheminformatics
Rajarshi Guha
5 February 2019

2018

Novel applications of Machine Learning in cheminformatics
Ola Spjuth
6 September 2018

2017

Helping to improve the practice of cheminformatics
Rajarshi Guha & Egon Willighagen

2013

Cheminformatics for the masses: a chance to increase educational opportunities for the next generation of cheminformaticians
David J Wild
5 July 2013

2012

InChI: connecting and navigating chemistry
Antony J Williams
13 December 2012

Semantic physical science
Peter Murray-Rust & Henry S Rzepa
3 August 2012

2011

Semantic science and its communication - a personal view
Peter Murray-Rust
14 October 2011

Resource description framework technologies in chemistry
Egon L Willighagen & Martin P Brändle
13 May 2011

2009

Grand challenges for cheminformatics
David J Wild

Journal announcements

Benefit from our free funding service
We offer a free open access support service to make it easier for you to discover and apply for article-processing charge (APC) funding. Learn more here.

oa

Latest Tweets

Follow @jcheminf on X to get the latest updates from Journal of Cheminformatics!
New Content Item

BMC is part of Springer Nature

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 7.1
    5-year Journal Impact Factor: 9.3
    Source Normalized Impact per Paper (SNIP): 2.078
    SCImago Journal Rank (SJR): 1.745

    Speed 2024
    Submission to first editorial decision (median days): 9
    Submission to acceptance (median days): 131

    Usage 2024
    Downloads: 1,615,511
    Altmetric mentions: 886

    Citations
    Click here to see citation distribution in recent years