Disruption of mitochondrial oxidative phosphorylation by chidamide eradicates leukemic cells in AML
Authors (first, second and last of 4)

Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. In addition, the journal has a strong commitment to facilitating the transfer of knowledge from the basic laboratory to the clinical practice, with the publication of educational series devoted to closing the gap between molecular and clinical oncologists. Molecular biology of tumours, identification of biomarkers for cancer diagnosis, prognosis or prediction of treatment response, identification of new targets for cancer therapy, as well as development of new technologies for research and treatment of cancer are the major themes covered by both the educational series and research articles. A broad spectrum of subjects, including the molecular and cellular bases of disease, aetiology, pathophysiology, pathology, epidemiology, clinical features, and the diagnosis, prognosis and treatment of cancer, will be considered for publication.
This series focuses on adaptive therapy including alternative systemic treatment, radiotherapy, supportive therapy and palliative treatment options used to prolong life.
The connection between the Immune System and Cancer has been always there, but only recently, it has been possible to uncover some vulnerable targets of the system, check-point inhibitors among others, that look very promising in cancer treatment.
Check out the Topical Collection
This January Professor Gascón would like to highlight the following review articles. Papers that aren't open access will be free to access until the 15th September 2021.
The following article has been made free to access until the 28th Feb, to mark World Cancer Day
Research on CRISPR/system in major cancers and its potential
in cancer treatments
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