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Overview
Journal of Pharmacokinetics and Pharmacodynamics is a comprehensive resource covering all aspects of pharmacokinetics, pharmacodynamics, and the application of pharmacometrics to drug development and clinical care.
- Includes physiological-based pharmacokinetics (PBPK), and systems pharmacology (QSP).
- Presents both theoretical and experimental papers on a range of related topics.
- Considers applications of machine learning to pharmacokinetics-pharmacodynamics.
- Applies research findings to real-world observations.
- Official journal of the International Society of Pharmacometrics (ISoP).
- Editor-in-Chief
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- Peter Bonate
- Impact factor
- 2.5 (2022)
- 5 year impact factor
- 2.4 (2022)
- Submission to first decision (median)
- 8 days
- Downloads
- 285,145 (2023)
Societies and partnerships
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Latest articles
Journal updates
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In Memoriam: Hartmut Derendorf
The journal extends its condolences to the family of Editorial Advisory Board Member Hartmut Derendorf, who unexpectedly passed away on November 23, 2020. He was a leader in the field and he contributed to the journal as a reviewer and author. A commentary on his life and legacy was published in March 2021. His obituary can be found here.
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Journal of Pharmacokinetics and Pharmacodynamics Special Issue on Chronopharmacometrics
Chronopharmacology is part of pharmacology that is concerned with effects of biological rhythms while pharmacometrics relates to mathematical models of pharmacokinetics and pharmacodynamics of drugs. Chronopharmacometrics encompasses pharmacometric methods relevant to quantifying chronopharmacology and chronotherapeutics.
A special issue of Journal of Pharmacokinetics and Pharmacodynamics on Chronopharmacometrics was published in July 2021 presenting state-of-the-art modeling approaches that address the presence of biorhythms in biomarkers used in drug development and therapeutics. Potential topics included but were not limited to:
- Examples of drugs and biomarkers exhibiting biorhythms: genes, hormones, cells, physiological processes
- Cosinor analysis and other statistical approaches to detecting and quantifying rhythms in physiological baselines
- PKPD, PBPK, QSP models of drugs and drug effects with circadian rhythms
- Mixed effects models of biorhythmic data
- Time to event analysis of sleep/awake patterns
- Optimization of dosing regimens for drugs with circadian PKPD
- Machine learning methods for identification and quantification of biorhythms
- Real-time data collection of digital data and biorhythms
- Models of biorhythms in cell cycle
- Examples of software designed for analysis of biorhythmic data
Journal information
- Electronic ISSN
- 1573-8744
- Print ISSN
- 1567-567X
- Abstracted and indexed in
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- ANVUR
- BFI List
- BIOSIS
- Baidu
- Biological Abstracts
- CLOCKSS
- CNKI
- CNPIEC
- Chemical Abstracts Service (CAS)
- Chimica
- Current Contents/Life Sciences
- Dimensions
- EBSCO
- EMBASE
- Google Scholar
- Japanese Science and Technology Agency (JST)
- Medline
- Meta
- Naver
- OCLC WorldCat Discovery Service
- Portico
- ProQuest
- Reaxys
- SCImago
- SCOPUS
- Science Citation Index Expanded (SCIE)
- TD Net Discovery Service
- UGC-CARE List (India)
- Wanfang
- Copyright information
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