Call for Papers: Topical Collection on Biomaterials for in-vitro 3D models

Guest Editor: Joaquim Miguel Oliveira1, 2
Co-Guest Editor: Rui L. Reis1, 2

13B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Barco, Guimarães, Portugal;

2ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal.

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Dear Colleagues,

In vitro 3D models have been attracting a great deal of attention due to its versatility in basic research, but also due to its possible industrial and clinical applications. Accompanying this trend, the fundamental knowledge gained on the cell-extracellular matrix interactions is opening up new avenues for the use of different biomaterials in the development of reliable in vitro models. In the last few years, biomaterials processing methods such as 3D bioprinting have allowed producing constructs with diverse composition and architecture that, when cultured in dynamic culturing systems, are able to better mimic different tissues and user-friendly in vitro 3D models. These advanced in vitro models are now able to better meet the requirements of precision medicine, i.e. it allows high-throughput approaches and efficient drug screenings.

This Special Issue on “Biomaterials for in vitro models”, aims to overview the most significant contributions involving the use of different biomaterials as extracellular matrices for application in the development of in vitro models. The topics can comprise all aspects of biomaterials, including, but not limited to, the following subjects: i) Design, synthesis and functionalization of biomaterials (synthetic- and natural-based) to be used as extracellular matrices (ECM); ii) Processing and characterization of decellularized and cell-based matrices, scaffolds, hydrogels and bioinks to be used in in vitro models; iii) Design and development of spheroids, organoids and organ- and tumour-on-a-chip; iv) Methods comprising in vitro 3D platforms for drugs and nanomedicine testing and validation: v) Current developments and future trends on the use of in vitro 3D models in a wide range of medical applications, including precision medicine.

We kindly invite you to submit a manuscript(s) for this Special Issue. Full papers and concise reviews are welcome.