Biomarkers in Cancer

1. Front Matter

   Pages i-xxviii

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2. General Aspects: Techniques and Overviews

   1. Front Matter

      Pages 1-1

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   2. OMICS for Tumor Biomarker Research

      • Sergei Moshkovskii, Mikhail Pyatnitsky, Petr Lokhov, Ancha Baranova

      Pages 3-30

   3. Circulating Tumor Cells as Biomarkers in Cancer

      • James Freeman, Elin S. Gray, Mel Ziman

      Pages 31-51

   4. Oncoproteomic Approaches to Cancer Marker Discovery: The Case of Colorectal Cancer

      • Francesco Salvatore, Claudia Corbo, Marica Gemei, Luigi Del Vecchio

      Pages 53-71

   5. Cancer Cardiotoxicity and Cardiac Biomarkers

      • Michela Salvatici, Daniela Cardinale, Alessandro Colombo, Maria Teresa Sandri

      Pages 73-105

   6. DNA Methylation as a Biomarker in Cancer

      • Shinichi Fukushige, Akira Horii

      Pages 107-133

   7. Kallikreins as Biomarkers in Human Malignancies

      • Kleita Michaelidou, Athina Kladi-Skandali, Andreas Scorilas

      Pages 135-165

   8. MAP17 as Biomarker for Cancer Treatment

      • Amancio Carnero

      Pages 167-178

   9. CA 19-9 as a Serum Biomarker in Cancer

      • Kavya Krishna, Tanios Bekaii-Saab

      Pages 179-201

   10. PTTG (Securin) as Cancer Biomarker

       • Dimitrios N. Kanakis, Elmar Kirches

       Pages 203-231

   11. U2 Small Nuclear RNA as a Biomarker in Cancer

       • Stephan A. Hahn, Hannah Zoellner, Abdelouahid Maghnouj, Deepak B. Vangala

       Pages 233-250

3. Bladder, Kidney, Liver and Lung

   1. Front Matter

      Pages 251-251

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   2. Centrosome Amplification as Biomarkers in Bladder Cancer Using Touch Biopsy and Bladder Washing Cytological Specimens

      • Hideyasu Matsuyama

      Pages 253-272

   3. Microarrays and Renal Cell Cancer Biomarkers

      • Peter Schraml, Manfred Beleut

      Pages 273-301

   4. Immunogenic Cell Death Markers in Liver Cancer

      • Nikolaus Kohles, Stefan Holdenrieder

      Pages 303-324

   5. Epigenetics and Biomarkers in Lung Cancer: Emerging Blood-Based Molecular Biomarkers for Detection and Monitoring

      • Athina Markou, Ioanna Sourvinou, Ioanna Balkouranidou, Evi S. Lianidou

      Pages 325-344

   6. Maspin Staining and Its Use as Biomarker in Lung Cancer

      • Rossana Berardi, Francesca Morgese, Agnese Savini, Azzurra Onofri, Stefano Cascinu

      Pages 345-358

4. Brain

   1. Front Matter

      Pages 359-359

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   2. LGR5 as Marker in Brain Cancer

      • Susumu Nakata, Emma Phillips, Violaine Goidts

      Pages 361-378

The World Health Organisation have reported that each year on a global basis there are over 8 million deaths from cancer. This is 13% of all deaths. As well as those who die, there are many who are being treated for cancer. Some cancers, hitherto deemed to be incurable, can now be cured. Part of the overall package of healthcare related to cancer is the application of biomarkers.  Biomarkers can be used not only to determine stages and effects of cancer, but also to aid treatments regimes. Biomarkers in Cancer combines detailed information on cancer types and the use of biological indicators. It covers the latest knowledge, trends and applications.  It links conventional approaches with new platforms

• Application to prognosis
• Biomarkers in disease
• Cancer Research
• Discovery of biomarkers
• High throughput technologies

• Faculty of Life Sciences & Medicine King’s College London, Department of Nutrition and Dietetics Division of Diabetes & Nutritional Scien, London, United Kingdom

  Victor R. Preedy

• Faculty of Science & Technology, Department of Biomedical Sciences, University of Westminster, London, United Kingdom

  Vinood B. Patel

Professor Victor R. Preedy is a senior faculty member of King's College London (Professor of Nutritional Biochemistry) and King's College Hospital (Professor of Clinical Biochemistry). He is attached to both the Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics. He is also Director of the Genomics Centre and a member of the School of Medicine. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1993 he gained his second doctoral degree, for his outstanding contribution to protein metabolism in health and disease. He has received membership and fellowship of a number of academic and professional bodies in the UK, including the Royal College of Pathologists, the Royal Institute of Public Health, and the Royal Society of Chemistry. Professor Preedy has published over 570 articles, which includes 165 peer-reviewed manuscripts based on original research, 100 reviews, and over 50 books and book volumes.

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