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Lecture Notes (Scuola Normale Superiore)

Transcriptome Analysis

Introduction and Examples from the Neurosciences

Authors: Cellerino, Alessandro, Sanguanini, Michele

  • Serves as a guide to biological interpretation of complex data
    Written with experimental and data-oriented scientists in mind, it presents both the quantitative and qualitative aspects of transcriptome analysis 
    Spans topics from basic methods, like plotting data, to more advanced ones, such as network analysis 
    Provides extensive applications and biological interpretation of transcriptome analysis

Buy this book

eBook 20,22 €
price for Italia (gross)
  • ISBN 978-88-7642-642-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 27,04 €
price for Italia (gross)
  • Atteso per: 20 agosto 2018
  • ISBN 978-88-7642-641-4
  • Free shipping for individuals worldwide
About this Textbook

The goal of this book is to be an accessible guide for undergraduate and graduate students to the new field of data-driven biology. Next-generation sequencing technologies have put genome-scale analysis of gene expression into the standard toolbox of experimental biologists. Yet, biological interpretation of high-dimensional data is made difficult by the lack of a common language between experimental and data scientists. By combining theory with practical examples of how specific tools were used to obtain novel insights in biology, particularly in the neurosciences, the book intends to teach students how to design, analyse, and extract biological knowledge from transcriptome sequencing experiments.
Undergraduate and graduate students in biomedical and quantitative sciences will benefit from this text as well as academics untrained in the subject.

About the authors

Alessandro Cellerino received a PhD in Neurobiology from Scuola Normale Superiore, Pisa, Italy. After continuing his research in various institutions, including Max-Planck Institut für Psychiatrie, Martinsried, Germany; University of Tübingen, Forschungsstelle für experimentelle Ophthalmologie; and CNR, Institute of Neurophysiology, Pisa, he returned to Scuola Normale Superiore as assistant professor, was visiting scientist and junior group leader at the Leibniz Institute on Aging, Jena and was later promoted to associate professor at Scuola Normale. He is also leader of a cooperation research group between Scuola Normale Superiore and the Leibniz Institute on Aging, Jena.

Alessandro Cellerino's scientific interests relate to neuroscience, biology of aging and functional genomics. He has published a monograph and numerous articles within these fields and he teaches neurogenomics and biology of aging.

 
Michele Sanguanini is a member of Gonville & Caius College, a PhD candidate at the Centre for Misfolding Diseases (Department of Chemistry, University of Cambridge), and a Scuola Normale Superiore graduate. His research involves the systems biology and biophysics underlying neurodegenerative processes and ageing, with a focus on protein aggregation in Alzheimer’s disease.

Table of contents (9 chapters)

  • A primer on data distributions and their visualisation

    Cellerino, Alessandro (et al.)

    Pages 1-10

    Preview Buy Chapter 30,44 €
  • Next-generation RNA sequencing

    Cellerino, Alessandro (et al.)

    Pages 11-25

    Preview Buy Chapter 30,44 €
  • RNA-seq raw data processing

    Cellerino, Alessandro (et al.)

    Pages 27-44

    Preview Buy Chapter 30,44 €
  • Differentially expressed gene detection and analysis

    Cellerino, Alessandro (et al.)

    Pages 45-58

    Preview Buy Chapter 30,44 €
  • Unbiased clustering methods

    Cellerino, Alessandro (et al.)

    Pages 59-83

    Preview Buy Chapter 30,44 €

Buy this book

eBook 20,22 €
price for Italia (gross)
  • ISBN 978-88-7642-642-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 27,04 €
price for Italia (gross)
  • Atteso per: 20 agosto 2018
  • ISBN 978-88-7642-641-4
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Transcriptome Analysis
Book Subtitle
Introduction and Examples from the Neurosciences
Authors
Series Title
Lecture Notes (Scuola Normale Superiore)
Series Volume
17
Copyright
2018
Publisher
Edizioni della Normale
Copyright Holder
Scuola Normale Superiore Pisa
eBook ISBN
978-88-7642-642-1
DOI
10.1007/978-88-7642-642-1
Softcover ISBN
978-88-7642-641-4
Edition Number
1
Number of Pages
XIV, 188
Topics