Overview
Covers fundamental aspects of sequence analysis in evolutionary biology, such as sequence alignment, phylogeny reconstruction, and coalescent simulation
Covers the material exclusively through 400 computer problems to enable learning by doing
Offers solutions to all problems to encourage self-study at a pace determined by the student
Contains over 30 programs written specifically for this book, which are provided as source code for further study
Ensures long-term usability of the course material by concentrating on fundamental concepts and utilizing the UNIX command line
Includes supplementary material: sn.pub/extras
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Table of contents (9 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level, to enable learning by doing. Students solve the problems in the same computational environment used for decades in science – the UNIX command line. This is available on all three major operating systems for PCs: Microsoft Windows, Mac-OSX, and Linux. To learn using this powerful system, students analyze sample sequence data by applying generic tools, bioinformatics software, and over 40 programs specifically written for this course. The solutions for all problems are included, making the book ideal for self-study. Problems are grouped into sections headed by an introduction and a list of new concepts and programs. By using practical computing to explore evolutionary concepts and sequence data, the book enables readers to tackle their own computational problems.
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Authors and Affiliations
About the authors
Bernhard Haubold studied Natural Sciences at Cambridge University, UK and completed his DPhil in Bacterial opulation Genetics at Oxford University, UK in 1998. After training as a Post-Doc at the Max-Planck-Institute for Chemical Ecology in Jena, Germany he worked in the biotech industry before taking on a professorship in Bioinformatics at the University of Applied Sciences, Weihenstephan, Germany in 2003. In 2008, he moved to his current post as a researcher at the Max-Planck-Institute for Evolutionary Biology in Plön, Germany. He also teaches Bioinformatics at Lübeck University. Together with Thomas Wiehe he is the author of Introduction to Computational Biology, An Evolutionary Approach, which was published by Birkhäuser in 2006.
Angelika Börsch-Haubold studied Pharmacy at Freiburg University, Germany and Pharmacology at Cambridge University, UK. She completed her DPhil in Pharmacology at Oxford University, UK in 1997, prior to remaining at Oxford for a junior research fellowship. From 2005 to 2008, she taught various courses at the University of Applied Sciences, Weihenstephan, Germany. From 2008 to 2014 she worked as a researcher at the Max-Planck-Institute for Evolutionary Biology in Plön, Germany. She has contributed teaching material to Science in School and was involved in translating the fifth edition of The Molecular Biology of the Cell into German.
Bibliographic Information
Book Title: Bioinformatics for Evolutionary Biologists
Book Subtitle: A Problems Approach
Authors: Bernhard Haubold, Angelika Börsch-Haubold
DOI: https://doi.org/10.1007/978-3-319-67395-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Softcover ISBN: 978-3-319-88424-0Published: 06 June 2019
eBook ISBN: 978-3-319-67395-0Published: 23 January 2018
Edition Number: 1
Number of Pages: XIII, 318
Number of Illustrations: 22 b/w illustrations, 22 illustrations in colour
Topics: Bioinformatics, Evolutionary Biology, Computational Biology/Bioinformatics, Computer Appl. in Life Sciences