Advances in Experimental Medicine and Biology

Intrinsically Disordered Proteins Studied by NMR Spectroscopy

Editors: Felli, Isabella C., Pierattelli, Roberta (Eds.)

Free Preview
  • Focuses on Intrinsically Disordered Proteins studied by NMR Spectroscopy
  • Chapters written by partners of the Marie Curie Initial Training Network
  • The study of intrinsically disordered proteins has seen explosive growth over the past five to ten years
see more benefits

Buy this book

eBook 107,09 €
price for Italia (gross)
  • ISBN 978-3-319-20164-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 155,99 €
price for Italia (gross)
  • ISBN 978-3-319-20163-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover 136,06 €
price for Italia (gross)
  • ISBN 978-3-319-37117-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrinsic protein disorder is now recognized as one of the key features for a large variety of cellular functions, where structural flexibility presents a functional advantage in terms of binding plasticity and promiscuity and this volume explores this exciting new research.

Recent progress in the field has radically changed our perspective to study IDPs through NMR: increasingly complex IDPs can now be characterized, a wide range of observables can be determined reporting on the structural and dynamic properties, computational methods to describe the structure and dynamics are in continuous development and IDPs can be studied in environments as complex as whole cells. This volume communicates the new exciting possibilities offered by NMR and presents open questions to foster further developments.

Intrinsically Disordered Proteins Studied by NMR Spectroscopy provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Back to the Future: Nuclear Magnetic Resonance and Bioinformatics Studies on Intrinsically Disordered Proteins

    Dunker, A. Keith (et al.)

    Pages 1-34

  • Structure and Dynamics of Intrinsically Disordered Proteins

    Fu, Biao (et al.)

    Pages 35-48

  • NMR Methods for the Study of Instrinsically Disordered Proteins Structure, Dynamics, and Interactions: General Overview and Practical Guidelines

    Brutscher, Dr. Bernhard (et al.)

    Pages 49-122

  • Ensemble Calculation for Intrinsically Disordered Proteins Using NMR Parameters

    Kragelj, Jaka (et al.)

    Pages 123-147

  • NMR Spectroscopic Studies of the Conformational Ensembles of Intrinsically Disordered Proteins

    Kurzbach, Dennis (et al.)

    Pages 149-185

Buy this book

eBook 107,09 €
price for Italia (gross)
  • ISBN 978-3-319-20164-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 155,99 €
price for Italia (gross)
  • ISBN 978-3-319-20163-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover 136,06 €
price for Italia (gross)
  • ISBN 978-3-319-37117-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Intrinsically Disordered Proteins Studied by NMR Spectroscopy
Editors
  • Isabella C. Felli
  • Roberta Pierattelli
Series Title
Advances in Experimental Medicine and Biology
Series Volume
870
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-20164-1
DOI
10.1007/978-3-319-20164-1
Hardcover ISBN
978-3-319-20163-4
Softcover ISBN
978-3-319-37117-7
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIII, 421
Number of Illustrations
13 b/w illustrations, 98 illustrations in colour
Topics