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Prevention and Treatment of Atherosclerosis

Improving State-of-the-Art Management and Search for Novel Targets

  • Summarizes the latest studies on the management of cardiovascular risk factors
  • Reviews exhaustively the key recent research into the pathogenesis of atherosclerotic cardiovascular diseases
  • Outlines various strategies of identifying and validating novel targets for prevention and treatment of atherosclerosis
  • This book is open access, which means that you have free and unlimited access

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 270)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-x
  2. Improving the Treatment of Established Targets

    1. Front Matter

      Pages 1-1
    2. Diet, Lifestyle, Smoking

      • Lale Tokgozoglu, Vedat Hekimsoy, Giuseppina Costabile, Ilaria Calabrese, Gabriele Riccardi
      Pages 3-24Open Access
    3. Blood Pressure-Lowering Therapy

      • Isabella Sudano, Elena Osto, Frank Ruschitzka
      Pages 25-45Open Access
    4. Glycaemic Control in Diabetes

      • D. Müller-Wieland, J. Brandts, M. Verket, N. Marx, K. Schütt
      Pages 47-71Open Access
    5. LDL-Cholesterol-Lowering Therapy

      • Angela Pirillo, Giuseppe D. Norata, Alberico L. Catapano
      Pages 73-101Open Access
    6. Antithrombotic Therapy: Prevention and Treatment of Atherosclerosis and Atherothrombosis

      • R. H. Olie, P. E. J. van der Meijden, H. M. H. Spronk, H. ten Cate
      Pages 103-130Open Access
  3. Novel Drug Developments Addressing Predefined Targets

    1. Front Matter

      Pages 131-131
    2. Metabolism of Triglyceride-Rich Lipoproteins

      • Jan Borén, Marja-Riitta Taskinen
      Pages 133-156Open Access
    3. High Density Lipoproteins: Is There a Comeback as a Therapeutic Target?

      • Arnold von Eckardstein
      Pages 157-200Open Access
    4. Lipoprotein(a)

      • Florian Kronenberg
      Pages 201-232Open Access
    5. Nonalcoholic Fatty Liver Disease

      • Lingling Ding, Yvonne Oligschlaeger, Ronit Shiri-Sverdlov, Tom Houben
      Pages 233-269Open Access
  4. Hypothesis Based Approaches to Unravel Novel Targets

    1. Front Matter

      Pages 287-287
    2. Novel Adipose Tissue Targets to Prevent and Treat Atherosclerosis

      • Ludger Scheja, Joerg Heeren
      Pages 289-310Open Access
    3. Microbiome and Cardiovascular Disease

      • Hilde Herrema, Max Nieuwdorp, Albert K. Groen
      Pages 311-334Open Access
    4. Smooth Muscle Cell-Proteoglycan-Lipoprotein Interactions as Drivers of Atherosclerosis

      • Sima Allahverdian, Carleena Ortega, Gordon A. Francis
      Pages 335-358Open Access
    5. Anti-inflammatory and Immunomodulatory Therapies in Atherosclerosis

      • Justine Deroissart, Florentina Porsch, Thomas Koller, Christoph J. Binder
      Pages 359-404Open Access
    6. Neutrophil Extracellular Traps in Atherosclerosis and Thrombosis

      • Thomas M. Hofbauer, Anna S. Ondracek, Irene M. Lang
      Pages 405-425Open Access
  5. Hypothesis-free Approaches to Unravel Novel Targets

    1. Front Matter

      Pages 427-427

About this book

This open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume 'Atherosclerosis: Diet and Drugs'  reflects the state-of-the-art and most recent developments in atherosclerosis research. Outstanding international experts give a comprehensive overview of the field covering topics, such as improving the treatment focusing on established targets, novel drug developments addressing pre-defined targets, hypothesis-based and hypothesis-free approaches to unravel novel targets. 

Editors and Affiliations

  • Institute of Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland

    Arnold von Eckardstein

  • Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria

    Christoph J. Binder

About the editors

Previous publications in the Handbook of Experimental Pharmacology series co-edited by Prof. ​Arnold von Eckardstein : Atherosclerosis: Diet and Drugs, 2005, Arnold von Eckardstein; High Density Lipoproteins, 2015, Arnold von Eckardstein, Dimitris Kardassis (eds.), Open Access

Bibliographic Information

  • Book Title: Prevention and Treatment of Atherosclerosis

  • Book Subtitle: Improving State-of-the-Art Management and Search for Novel Targets

  • Editors: Arnold von Eckardstein, Christoph J. Binder

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-030-86076-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s) 2022

  • Hardcover ISBN: 978-3-030-86075-2Published: 01 February 2022

  • Softcover ISBN: 978-3-030-86078-3Published: 01 February 2022

  • eBook ISBN: 978-3-030-86076-9Published: 31 January 2022

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: X, 538

  • Number of Illustrations: 3 b/w illustrations, 37 illustrations in colour

  • Topics: Cardiology, Pharmacology/Toxicology, Angiology, Metabolic Diseases

Buy it now

Buying options

Softcover Book USD 49.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 59.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access