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Fundamental Biomedical Technologies

Intracellular Delivery

Fundamentals and Applications

Editors: Prokop, Ales (Ed.)

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  • Comprehensive set of reviews dealing with mechanisms of uptake by cells and tissues
  • Covering several key chemical areas of preparation of nanovehicles
  • Delivers some important application areas in medicine
  • Written by world experts in this field
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eBook 236,81 €
price for India (gross)
  • ISBN 978-94-007-1248-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 279,99 €
price for India (gross)
  • ISBN 978-94-007-1247-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact significantly existing conservative practices.

This volume is a collection of authoritative reviews. In the introductory part we define the field (intracellular delivery). Then, we first we cover fundamental routes of nanodelivery devices cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; all at academic and applied levels. Following is dedicated to enhancing delivery via special targeting motifs. Second, we introduce different types of intracellular nanodelivery devices (their chemistry, although the coverage is far from complete) and ways of producing these different devices. Third, we put special emphasis on particular disease states and on other biomedical applications. Diagnostic and sensing is also included.

The intracellular delivery/therapy is a very pregnant topic which will stir great interest. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is a great potential for targeted delivery with improved localized delivery and efficacy.

Table of contents (26 chapters)

Table of contents (26 chapters)
  • Mass Transport via Cellular Barriers and Endocytosis

    Pages 3-55

    Ferrati, Silvia (et al.)

  • Approaches to Achieving Sub-cellular Targeting of Bioactives Using Pharmaceutical Nanocarriers

    Pages 57-72

    Solomon, Melani (et al.)

  • Delivery to Intracellular Targets by Nanosized Particles

    Pages 73-95

    Barratt, Gillian

  • The Potential and Current Progress of Internalizing Molecules in Targeted Drug Delivery

    Pages 97-123

    Zhou, Jiehua (et al.)

  • Simulation Based Analysis of Nanocarrier Internalization: Exciting Challenges with a New Computational Tool

    Pages 125-154

    Csukás, Béla (et al.)

Buy this book

eBook 236,81 €
price for India (gross)
  • ISBN 978-94-007-1248-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 279,99 €
price for India (gross)
  • ISBN 978-94-007-1247-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Intracellular Delivery
Book Subtitle
Fundamentals and Applications
Editors
  • Ales Prokop
Series Title
Fundamental Biomedical Technologies
Series Volume
5
Copyright
2011
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-94-007-1248-5
DOI
10.1007/978-94-007-1248-5
Hardcover ISBN
978-94-007-1247-8
Series ISSN
1559-7083
Edition Number
1
Number of Pages
XIX, 867
Number of Illustrations
186 b/w illustrations, 95 illustrations in colour
Topics