Dystonia and Dystonic Syndromes

1. Front Matter

   Pages i-ix

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2. Pathophysiology and Nosology of Dystonia

   1. Front Matter

      Pages 1-1

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   2. Dystonia: The Syndrome, Its Term, Concept and Their Evolution

      • Petr Kanovsky, Raymond L. Rosales, Kailash P. Bhatia

      Pages 3-12

   3. Physiology of Dystonia

      • Giovanni Abbruzzese, Elisa Pelosin, Laura Avanzino

      Pages 13-25

   4. Genetics of Dystonia

      • Ana Westenberger, Christine Klein

      Pages 27-48

   5. Nosology and Classification of Dystonia

      • Ana Claudia Saraiva Ribeiro, Kailash P. Bhatia

      Pages 49-60

   6. Secondary Dystonia

      • Petr Kanovsky, Dirk Dressler, Kateřina Menšíková

      Pages 61-74

   7. Dystonia–Parkinsonism Syndromes

      • Ericka Samantha A. Teleg, Raymond L. Rosales

      Pages 75-88

   8. Dystonia in Multiple System Atrophy, Progressive Supranuclear Palsy, and Corticobasal Degeneration

      • Luca Marsili, Carlo Colosimo

      Pages 89-99

   9. Functional (Psychogenic) Dystonia

      • Antonella Macerollo, Mark J. Edwards

      Pages 101-113

3. Treatment of Dystonia

   1. Front Matter

      Pages 115-115

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   2. Traditional Pharmacotherapeutic Approaches to Dystonia: Mode of Action of Currently Used Drugs for the Treatment of Dystonia

      • Tarannum S. Khan, Hubert H. Fernandez

      Pages 117-125

   3. Botulinum Toxin Therapy of Dystonia

      • Dirk Dressler, Petr Kanovsky

      Pages 127-149

   4. Long-Term Treatment of Focal Dystonias (Cervical and Writer’s Cramp): Clinical and Quality of Life Impact

      • Martin Bareš, Marek Baláž, Pavel Filip

      Pages 151-164

   5. Surgical Treatment of Dystonia

      • Jürgen Voges

      Pages 165-185

   6. Pathophysiology of Dystonia: Models and Mechanisms

      • Claudia M. Hendrix, Jerrold L. Vitek

      Pages 187-207

   7. Neurorehabilitation in Dystonia

      • Jorge Hernandez Franco, Raymond L. Rosales

      Pages 209-226

   8. Dystonia in Art: The Impact of Psychiatric and Neurological Disease on the Work of the Sculptor F. X. Messerschmidt

      • Michal Maršálek

      Pages 227-244

4. Back Matter

   Pages 245-253

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The current concept of dystonic movement connects the abnormal function of somatosensory pathways and somatosensory analyzers with the dystonic performance of motor action, which is based on the abnormality of sensorimotor integration. This concept is reflected not only in idiopathic dystonia, but also in secondary and symptomatic dystonias. This book will give a comprehensive account of the history of the terms dystonia and dystonic, the physiology of dystonic movement and the genetics and clinical appearance of primary and secondary dystonias. Taking into consideration latest research findings, Dystonia and Dystonic Syndromes offers an in-depth discussion of current treatment options available for dystonia, including pharmacotherapy, surgery and neurorehabilitation. Therefore, it serves as a valuable reference for practitioners in the fields of neurology, neurosurgery, psychiatry and neuroradiology as well as for neuroscientists.

• botulinum toxin therapy
• dystonia diagnosis
• dystonia surgery
• dystonia treatment
• dystonic disorders
• movement disorders

• Department of Neurology, Palacky University Medical School University Hospital Olomouc, Olomouc, Czech Republic

  Petr Kanovsky

• Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, London, United Kingdom

  Kailash P. Bhatia

• Department of Neurology and Psychiatry, The Royal and Pontifical University of Santo Tomas, Manila, Philippines

  Raymond L. Rosales

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