Overview
- State-of-the art guide of metabolism focused on host-pathogen interactions
- Characterization of the emerging role of immunometabolism during infections
- Comparative description of microbial auxotrophy and host cell metabolic rewiring by pathogens;
- Current status and future perspectives on the clinical application of cell metabolism evaluation in infectious contexts
Part of the book series: Experientia Supplementum (EXS, volume 109)
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Table of contents (13 chapters)
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Front Matter
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A Guide of Metabolism During Host–Pathogen Interactions
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Front Matter
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Microbial Metabolic Adaptation and Pathogen Rewiring of Host Cell Metabolism During Infection
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Front Matter
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Keywords
About this book
This book focuses on host–pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.
Editors and Affiliations
About the editors
Egídio Torrado is Assistant Researcher at the Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Portugal. His research is focused on the mechanisms that regulate the protective immune response to Mycobacterium tuberculosis
both during the innate and chronic phases of the infection. The emphasis of his work is on cytokines and the maintenance of the T cell response and the development of pathological consequences to the host.
Bibliographic Information
Book Title: Metabolic Interaction in Infection
Editors: Ricardo Silvestre, Egídio Torrado
Series Title: Experientia Supplementum
DOI: https://doi.org/10.1007/978-3-319-74932-7
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-74931-0Published: 18 April 2018
Softcover ISBN: 978-3-030-09108-8Published: 03 January 2019
eBook ISBN: 978-3-319-74932-7Published: 06 April 2018
Series ISSN: 1664-431X
Series E-ISSN: 2504-3692
Edition Number: 1
Number of Pages: VIII, 476
Number of Illustrations: 2 b/w illustrations, 43 illustrations in colour
Topics: Molecular Medicine, Biochemistry, general, Medical Microbiology