Overview
- Illustrates the importance and function of different types of glycosylation in humans, written by experts in the field
- Reviews the role of glycosylation process in the pathophysiology of different diseases
- Explores the newest research on glycosylation of biotherapeutics
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1325)
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Table of contents (18 chapters)
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Front Matter
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Importance and Functions of the Human Glycome
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Front Matter
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Glycosylation in Disease
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Front Matter
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Keywords
About this book
Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans.
The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.
Editors and Affiliations
About the editors
Irena Trbojevic-Akmacic received her degree in Biochemistry and Analytical Chemistry at Faculty of Science, University of Zagreb in 2012 and her PhD degree in Biochemistry at the same University in 2015. Currently, she is working as a Head of UPLC Laboratory for Glycan Analysis in Genos Ltd, a private research organization that specializes in high-throughput glycomic analysis. Her research activities primarily focus on methods development for high-throughput N-glycan analysis and their application in population, genetic, epidemiologic and clinical glycomic studies. She has published 40 scientific papers in peer-reviewed international journals and participated in number of scientific trainings and conferences with oral and poster presentations.
Bibliographic Information
Book Title: The Role of Glycosylation in Health and Disease
Editors: Gordan Lauc, Irena Trbojević-Akmačić
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-70115-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021
Hardcover ISBN: 978-3-030-70114-7Published: 09 September 2021
Softcover ISBN: 978-3-030-70117-8Published: 10 September 2022
eBook ISBN: 978-3-030-70115-4Published: 08 September 2021
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XXV, 376
Number of Illustrations: 9 b/w illustrations, 37 illustrations in colour
Topics: Cell Biology, Protein Science, Genetics and Genomics, Medical Biochemistry, Biomedicine, general