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Macromolecular Protein Complexes III: Structure and Function

  • Book
  • © 2021

Overview

Editors:
  1. J. Robin Harris

    1. Institute of Molecular Physiology, University of Mainz, Mainz, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Jon Marles-Wright

    1. School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Broadens understanding of the biochemistry of a variety of macromolecular protein complexes
  • Addresses both structural and functional aspects
  • Is richly illustrated with molecular models derived from X-ray diffraction and Cryo-EM data

Part of the book series: Subcellular Biochemistry (SCBI, volume 96)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. Structure, Dynamics and Function of the 26S Proteasome

    • Youdong Mao
    Pages 1-151Open Access

  3. Factor VIII and Factor V Membrane Bound Complexes

    • Svetla Stoilova-McPhie
    Pages 153-175

  4. An Overview of Dps: Dual Acting Nanovehicles in Prokaryotes with DNA Binding and Ferroxidation Properties

    • Sunanda Margrett Williams, Dipankar Chatterji
    Pages 177-216

  5. Structure and Function of the Separase-Securin Complex

    • Shukun Luo, Liang Tong
    Pages 217-232

  6. The DNA Replication Machine: Structure and Dynamic Function

    • Nina Y. Yao, Michael E. O’Donnell
    Pages 233-258

  7. Recent Progress in Structural Studies on the GT-C Superfamily of Protein Glycosyltransferases

    • Heather Bohl, Lin Bai, Huilin Li
    Pages 259-271

  8. How Structures of Complement Complexes Guide Therapeutic Design

    • Jasmine K. Bickel, Tomas B. Voisin, Edward W. Tate, Doryen Bubeck
    Pages 273-295

  9. Architecture and Assembly of the Bacterial Flagellar Motor Complex

    • Yusuke V. Morimoto, Tohru Minamino
    Pages 297-321

  10. Cellulosomes: Highly Efficient Cellulolytic Complexes

    • Victor D. Alves, Carlos M. G. A. Fontes, Pedro Bule
    Pages 323-354

  11. Leucine Dehydrogenase: Structure and Thermostability

    • Hiroki Yamaguchi, Akiko Kamegawa, Kunio Nakata, Tatsuki Kashiwagi, Yoshinori Fujiyoshi, Kazutoshi Tani et al.
    Pages 355-372

  12. Structure, Function and Physiology of 5-Hydroxytryptamine Receptors Subtype 3

    • Eric Gibbs, Sudha Chakrapani
    Pages 373-408

  13. The SF3b Complex is an Integral Component of the Spliceosome and Targeted by Natural Product-Based Inhibitors

    • Nicholas A. Larsen
    Pages 409-432

  14. Interaction Networks of Ribosomal Expansion Segments in Kinetoplastids

    • Quentin Vicens, Anthony Bochler, Amy Jobe, Joachim Frank, Yaser Hashem
    Pages 433-450

  15. Hepatitis B Core Protein Capsids

    • Bettina Böttcher
    Pages 451-470

  16. Fibrinogen and Fibrin

    • Rustem I. Litvinov, Marlien Pieters, Zelda de Lange-Loots, John W. Weisel
    Pages 471-501

  17. Structural Organization and Protein-Protein Interactions in Human Adenovirus Capsid

    • Vijay S. Reddy, Michael A. Barry
    Pages 503-518

  18. A Structural Perspective on Gene Repression by Polycomb Repressive Complex 2

    • Xin Liu
    Pages 519-562

  19. Assembly and Function of the Anthrax Toxin Protein Translocation Complex

    • Robert C. Liddington
    Pages 563-577
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Keywords

About this book

This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few.

The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority.

Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Editors and Affiliations

  • Institute of Molecular Physiology, University of Mainz, Mainz, Germany

    J. Robin Harris

  • School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, UK

    Jon Marles-Wright

About the editors

Dr J. Robin Harris is a retired biochemist with specialism in macromolecular electron microscopy, now based in the UK.  He is the long-standing Series Editor of Subcellular Biochemistry. He is an Honorary Professor of the University of Mainz.

Dr Jon Marles-Wright is a Senior Lecturer in the School of Natural and Environmental Sciences at Newcastle University. He has broad interest and experience in biomolecular X-ray  crystallography and cryoelectron microscopy.

Bibliographic Information

  • Book Title: Macromolecular Protein Complexes III: Structure and Function

  • Editors: J. Robin Harris, Jon Marles-Wright

  • Series Title: Subcellular Biochemistry

  • DOI: https://doi.org/10.1007/978-3-030-58971-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-58970-7Published: 01 December 2020

  • Softcover ISBN: 978-3-030-58973-8Published: 02 December 2021

  • eBook ISBN: 978-3-030-58971-4Published: 30 November 2020

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 1

  • Number of Pages: VIII, 577

  • Number of Illustrations: 9 b/w illustrations, 157 illustrations in colour

  • Topics: Protein Science, Life Sciences, general, Cell Biology

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