Overview
- Authors:
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Lynda H. Powell
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Department of Preventive Medicine, Rush University Medical Center, Chicago, USA
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Kenneth E. Freedland
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Department of Psychiatry, Washington University in St. Louis, St. Louis, USA
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Peter G. Kaufmann
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College of Nursing, Villanova University, Villanova, USA
First comprehensive book on basic principles in the design and conduct of behavioral RCTs aimed at preventing or managing chronic diseases
Aims to promote same level of rigor in behavioral RCTs that is characteristic of double-blind drug RCTs
Integrates wisdom from the scientific method and influential behavioral trials to offer new directions and opportunities for the future
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Table of contents (12 chapters)
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Front Matter
Pages i-xviii
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 1-10
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 11-25
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 27-68
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 69-96
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 97-124
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 125-146
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 147-167
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 169-207
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 209-236
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 237-260
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 261-279
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- Lynda H. Powell, Peter G. Kaufmann, Kenneth E. Freedland
Pages 281-284
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Back Matter
Pages 285-314
About this book
This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.
Authors and Affiliations
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Department of Preventive Medicine, Rush University Medical Center, Chicago, USA
Lynda H. Powell
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Department of Psychiatry, Washington University in St. Louis, St. Louis, USA
Kenneth E. Freedland
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College of Nursing, Villanova University, Villanova, USA
Peter G. Kaufmann
About the authors
Linda Powell, PhD is chair of the Department of Preventive Medicine and the Charles J and Margaret Roberts Professor of Preventive Medicine, Medicine (Cardiology), Behavioral Sciences, and Pharmacology at Rush Medical College. She received her doctoral degree at Stanford University, conducted post-doctoral work in cardiovascular epidemiology at the University of California San Francisco, and began her academic career at Yale University's School of Public Health. Her research interests are dietary and other preventive risk factors in the development of chronic disesaes and problems of older persons, including Alzheimer's disease, cognitive decline, and cardiovascular diseases. Dr. Powell is an internationally recognized expert in the conduct of behavioral clinical trials aimed at changing behavior as a way to reduce risk of chronic disease. She is a member of the Society of Behavioral Medicine and the American Psychiatric Association.
