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  • Conference proceedings
  • © 2009

Mathematics of DNA Structure, Function and Interactions

  • Timely volume on mathematics of DNA structure
  • Color images throughout
  • Includes supplementary material: sn.pub/extras

Part of the book series: The IMA Volumes in Mathematics and its Applications (IMA, volume 150)

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Table of contents (17 papers)

  1. Front Matter

    Pages i-xi
  2. Nick Cozzarelli: A Personal Remembrance

    • Stephen D. Levene, Lynn Zechiedrich
    Pages 1-5
  3. Perspectives On DNA Looping

    • Laura Finzi
    Pages 53-71
  4. Differences Between Positively and Negatively Supercoiled DNA that Topoisomerases May Distinguish

    • Jonathan M. Fogg, Daniel J. Catanese Jr, Graham L. Randall, Michelle C. Swick, Lynn Zechiedrich
    Pages 73-121
  5. Calibration of Tethered Particle Motion Experiments

    • Lin Han, Bertrand H. Lui, Seth Blumberg, John F. Beausang, Philip C. Nelson, Rob Phillips
    Pages 123-138
  6. Difference Topology: Analysis of High-Order DNA-Protin Assemblies

    • Makkuni Jayaram, Rasika Harshey
    Pages 139-158
  7. Useful Intrusions of DNA Topology Into Experiments on Protein-DNA Geometry

    • Jason D. Kahn, James R. Jenssen, Vasavi Vittal
    Pages 159-175
  8. Topological Analysis of DNA-Protein Complexes

    • Soojeong Kim, Isabel K. Darcy
    Pages 177-194
  9. Four-Way Helical Junctions in DNA Molecules

    • David M.J. Lilley
    Pages 213-224
  10. Flexibility Of Nucleosomes On Topologically Constrained DNA

    • Andrei Sivolob, Christophe Lavelle, Ariel Prunell
    Pages 251-291
  11. Back Matter

    Pages 1-8

About this book

Propelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists.

Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give an overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.

Editors and Affiliations

  • Dept. Pharmacology & Genome Center, University of California, Davis, Davis, USA

    Craig John Benham

  • Dept. Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, USA

    Stephen Harvey

  • Dept. Chemistry & Chemical Biology, Rutgers State University of New Jersey, Piscataway, USA

    Wilma K. Olson

  • Dept. Mathematics, Florida State University, Tallahassee, USA

    De Witt Sumners

  • Dept. Mathematics, University of Pittsburgh, Pittsburgh, USA

    David Swigon

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access