Ni and Fe-Based Cross Coupling Reactions

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Article 1: Photoredox Catalysis in Nickel-Catalyzed Cross-Coupling

by Livia N. Cavalcanti, Gary A. Molander

The traditional transition metal-catalyzed cross-coupling reaction, although well suited for C(sp2)–C(sp2) cross-coupling, has proven less amenable toward coupling of C(sp3)-hybridized centers, particularly using functional group tolerant reagents and reaction conditions. The development of photoredox/Ni dual catalytic methods for cross-coupling has opened new vistas for the construction of carbon–carbon bonds at C(sp3)-hybridized centers. In this chapter, a general outline of the features of such processes is detailed.

Article 2: Fe-Catalyzed Cross-Dehydrogenative Coupling Reactions

by Leiyang Lv, Zhiping Li

Cross-dehydrogenative coupling (CDC), which enables the formation of carbon–carbon (C–C) and C–heteroatom bonds from the direct coupling of two C–H bonds or C–H/X–H bonds, represents a new state of the art in the field of organic chemistry. Iron, a prominent metal, has already shown its versatile application in chemical synthesis. This review attempts to provide a comprehensive understanding of the evolution of cross-dehydrogenative coupling via iron catalysis, as well as its application in synthetic chemistry.

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Guest Editor:

Arkaitz_CorreaArkaitz Correa studied Chemistry at the University of the Basque Country (UPV/EHU), where he finished his PhD in 2006 under the guidance of Prof. Esther Domínguez. During that time, he completed a 3-month stay at the University of Groningen in the group of Prof. Ben L Feringa. In 2007 he joined the group of Prof. Carsten Bolm at the RWTH Aachen University (Germany) as a postdoctoral researcher for 2 years. Then, he moved to the ICIQ (Tarragona) to undertake further postdoctoral studies with Prof. Ruben Martin (2008-2014). During that time, he also joined the group of Prof. J. M. Lassaletta to work in a collaborative project with Bayer CropScience at the CSIC (Seville). Through these years he has worked in several topics such as hypervalent iodine chemistry, metal-catalyzed cross-couplings and carbon dioxide fixation. In april 2014, he started his independent career at UPV/EHU as a Ramón y Cajal fellow and his current research interests are primarily focused on the field of C−H functionalization and heterocyclic chemistry.