Genetic Polymorphism and cancer susceptibility

Editors: Sameer, Aga Syed, Banday, Mujeeb Zafar, Nissar, Saniya (Eds.)

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  • Reviews the difference between genetic polymorphisms and mutations
  • Help in understanding the impact of SNPs on gene function
  • Reviews the role of genetic polymorphism in genetic predisposition to cancer
  • Discusses techniques used in the analysis of genetic polymorphism
  • Examines the genetic basis for individual variations in response to therapeutics
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eBook 117,69 €
price for Spain (gross)
  • ISBN 978-981-336-699-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 155,99 €
price for Spain (gross)
  • ISBN 978-981-336-698-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.

About the authors

Dr. Syed Sameer Aga is currently working as an Assistant Professor of Biochemistry in the Department of Basic Medical Sciences, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. He is also serving as the Chairman of the Quality Unit in College of Medicine, KSAU-HS. Dr. Syed is a life-time member of many societies related to genetics, molecular biology and medical education like the Association of Clinical Biochemists of India, Society of Indian Academy of Medical Genetics, Middle East Molecular Biology Sources, Asian Council of Science Editors, and Saudi Society of Medical Education, etc. He is also serving as the Associate Editor in three Journals, Frontiers in Oncology – Molecular Biosciences section, BioMed Research International, World Journal of Biological Chemistry and Current Drug Metabolism. He also serves as a full time reviewer for various journals including European Journal of Cancer Prevention (Lippincott Williams & Wilkins), PLOS One & PLOS Genetics (Public Library of Science), World Journal of Gastroenterology (Baishideng Publishing), Gene & Meta Gene (Elsevier Publishing), Bioscience Reports (Portland Press), Journal of Clinical Laboratory Analysis (John Wiley & Sons) and Tumor Biology (Sage Journals) etc. His research interests are focused on cancer biology and he has published more than seventy-five research and review articles in high repute journals with an h-index of 20 and authored ten books.

Dr. Mujeeb Zafar Banday is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. Dr. Banday has completed his Ph.D., M.Phil. and M.Sc. in Biochemistry from the University of Kashmir, J&K, India. He is serving as the review editor and associate reviewer  for the journal, Frontiers in Oncology - Cancer Epidemiology and Prevention (Frontiers Group) and full time reviewer for various journals including Gene (Elsevier Publishing), Bioscience Reports (Portland Press), BioMed Research International (Hindawi Publishing) and Toxicology and Environmental Health Sciences Review (Springer Nature). He has authored more than twenty research and review articles and three books.

Dr. Saniya Nissar is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. She has completed her PhD, MPhil, and MSc in clinical biochemistry from the University of Kashmir, J&K, India. She works as free-lancescientific content writer with many scientific magazines. She has published more than thirty research and review articles and authored four books. ​

Table of contents (10 chapters)

Table of contents (10 chapters)
  • Mutations and Polymorphisms: What Is The Difference?

    Pages 1-21

    Sameer, Aga Syed (et al.)

  • Single Nucleotide Polymorphisms and Pharmacogenomics

    Pages 23-52

    Arafah, Azher (et al.)

  • Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility

    Pages 53-77

    Yasmeen, Nusrath (et al.)

  • From Inflammation to Cancer: Role of Genetic Polymorphisms of Inflammatory Pathway Molecules in Gastric Cancer

    Pages 79-117

    Malli, Israa Abdullah

  • Colorectal Cancer and Genetic Polymorphism in Key Regulatory Low Penetrance Genes

    Pages 119-164

    Banday, Mujeeb Zafar (et al.)

Buy this book

eBook 117,69 €
price for Spain (gross)
  • ISBN 978-981-336-699-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 155,99 €
price for Spain (gross)
  • ISBN 978-981-336-698-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Genetic Polymorphism and cancer susceptibility
Editors
  • Aga Syed Sameer
  • Mujeeb Zafar Banday
  • Saniya Nissar
Copyright
2021
Publisher
Springer Singapore
Copyright Holder
The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-336-699-2
DOI
10.1007/978-981-33-6699-2
Hardcover ISBN
978-981-336-698-5
Edition Number
1
Number of Pages
XXI, 339
Number of Illustrations
2 b/w illustrations, 46 illustrations in colour
Topics